Results 11 to 20 of about 24,119 (207)

Influence of Extracellular Matrix Components on the Differentiation of Periodontal Ligament Stem Cells in Collagen I Hydrogel

open access: yesCells, 2023
Regeneration of periodontal tissues requires an integrated approach to the restoration of the periodontal ligament, cementum, and alveolar bone surrounding the teeth.
Alexey A. Ivanov   +5 more
doaj   +2 more sources

Decellularized Periodontal Ligament Cell Sheets with Recellularization Potential [PDF]

open access: yesJournal of Dental Research, 2014
The periodontal ligament is the key tissue facilitating periodontal regeneration. This study aimed to fabricate decellularized human periodontal ligament cell sheets for subsequent periodontal tissue engineering applications. The decellularization protocol involved the transfer of intact human periodontal ligament cell sheets onto ...
Farag, A.   +5 more
openaire   +6 more sources

The Experimental Study of Periodontal Ligament Stem Cells Derived Exosomes with Hydrogel Accelerating Bone Regeneration on Alveolar Bone Defect

open access: yesPharmaceutics, 2022
Introduction: this study was conducted to investigate the osteogenic ability of periodontal ligament stem cells (PDLSCs) derived exosomes (PDLSCs-Exos) and the effect of PDLSCs-Exos with hydrogel on alveolar bone defect repairment in the rat.
Yang Zhao   +5 more
doaj   +1 more source

Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

open access: yesStem Cells International, 2022
Background. Angiogenic tissue engineering is a vital problem waiting to be settled for periodontal regeneration. Erythropoietin, a multieffect cytokine, has been reported as a protective factor for cell fate.
Denghao Huang   +5 more
doaj   +1 more source

ILC1s and ILC3s Exhibit Inflammatory Phenotype in Periodontal Ligament of Periodontitis Patients

open access: yesFrontiers in Immunology, 2021
Innate lymphoid cells (ILCs) are emerging as important players in inflammatory diseases. The oral mucosal barrier harbors all ILC subsets, but how these cells regulate the immune responses in periodontal ligament tissue during periodontitis remains ...
Changyi Li   +9 more
doaj   +1 more source

Fibrillin-1 regulates periostin expression during maintenance of periodontal homeostasis

open access: yesJournal of Dental Sciences, 2022
Background/purpose: Human periodontal ligament consists of elastic system fibers, mainly fibrillin-1 (FBN1). Periostin (POSTN) maintains periodontal homeostasis.
Yoshikazu Manabe   +7 more
doaj   +1 more source

Roles of extracellular adenosine triphosphate on the functions of periodontal ligament cells

open access: yesBDJ Open, 2023
Objective Adenosine triphosphate (ATP) is an essential nucleotide that is normally present in both intracellular and extracellular compartments. Extracellular ATP (eATP) has a pivotal role in both physiological and pathological processes of periodontal ...
Maythwe Kyawsoewin   +5 more
doaj   +1 more source

Allogeneic Periodontal Ligament Stem Cell Therapy for Periodontitis in Swine     [PDF]

open access: yesStem Cells, 2010
AbstractPeriodontitis is one of the most widespread infectious diseases in humans. It is the main cause of tooth loss and associated with a number of systemic diseases. Until now, there is no appropriate method for functional periodontal tissue regeneration. Here, we establish a novel approach of using allogeneic periodontal ligament stem cells (PDLSCs)
Ding, Gang   +8 more
openaire   +2 more sources

Periodontal Ligament Stem Cells for Periodontal Regeneration [PDF]

open access: yesCurrent Oral Health Reports, 2015
Periodontal tissue is susceptible to chronic periodontal disease, which results in irreversible tissue destruction. Adult stem cells can be obtained from the periodontal ligament of the periodontium. Stem cells from the periodontal ligament (PDLSCs) are promising for periodontal regeneration because they can undergo guided differentiation under ...
In Seok Song   +5 more
openaire   +1 more source

3D Electrospun Polycaprolactone Scaffolds to Assess Human Periodontal Ligament Cells Mechanobiological Behaviour

open access: yesBiomimetics, 2023
While periodontal ligament cells are sensitive to their 3D biomechanical environment, only a few 3D in vitro models have been used to investigate the periodontal cells mechanobiological behavior.
Rémy Gauthier   +6 more
doaj   +1 more source

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