Results 241 to 250 of about 12,081 (284)

UCHL1 Impairs Periodontal Ligament Stem Cell Osteogenesis in Periodontitis

Journal of Dental Research, 2022
Periodontitis comprises a series of inflammatory responses resulting in alveolar bone loss. The suppression of osteogenesis of periodontal ligament stem cells (PDLSCs) by inflammation is responsible for impaired alveolar bone regeneration, which remains an ongoing challenge for periodontitis therapy.
L. Lin, S. Li, S. Hu, W. Yu, B. Jiang, C. Mao, G. Li, R. Yang, X. Miao, M. Jin, Y. Gu, E. Lu   +11 more
openaire   +2 more sources

Stem cell properties of human periodontal ligament cells

Journal of Periodontal Research, 2006
Background and Objective:  Stem cells have been used for regenerative therapies in various fields. The proportion of cells that possess stem cell properties in human periodontal ligament (PDL) cells is not yet well understood. In this study, we quantitatively characterized human PDL cells to clarify their stem cell properties, including self‐renewal ...
K, Nagatomo, M, Komaki, I, Sekiya, Y, Sakaguchi, K, Noguchi, S, Oda, T, Muneta, I, Ishikawa   +7 more
openaire   +2 more sources

Periodontal Ligament Stem Cells: An Overview

Journal of Oral Biosciences, 2010
Adult postnatal stem cells are multipotent and can be experimentally induced to differentiate into various specialized cell lineages. This has generated considerable interest in the arena of stem cell-based therapeutics. The identification of stem cells within the periodontal ligament represents a significant development in this regard.
Aneesha Acharya, Sharath Shetty, Vijay Deshmukh   +2 more
openaire   +1 more source

Periodontal Ligament Stem Cell Isolation Protocol: A Systematic Review

Current Stem Cell Research & Therapy, 2022
Abstract: Despite the plethora of literature regarding isolation and characterization of periodontal ligament stem cells (PDLSCs), due to the existence of controversies in the results, in this comprehensive review, we aimed to summarize and compare the effect of isolation methods on PDLSC properties, including clonogenicity, viability/proliferation ...
Maryam Rezai Rad, Fazele Atarbashi-Moghadam, Pouya Khodayari, Soran Sijanivandi   +3 more
openaire   +2 more sources

Characterization of Stem Cells from Alveolar Periodontal Ligament

Tissue Engineering Part A, 2011
Complete and predicable regeneration of complex periodontal structures, which include cementum, periodontal ligament (PDL), and alveolar bone, has been a great challenge for periodontal researchers. It is generally believed that human PDL from the root surface contains stem cells (r-PDLSCs), which can enhance cementum/PDL-like tissues regeneration in ...
Lei, Wang, Huan, Shen, Wei, Zheng, Liang, Tang, Zhenhua, Yang, Yuan, Gao, Qingtian, Yang, Chen, Wang, Yinzhong, Duan, Yan, Jin   +9 more
openaire   +2 more sources

Immunomodulatory properties of human periodontal ligament stem cells

Journal of Cellular Physiology, 2009
AbstractTissue engineering utilizing periodontal ligament stem cells (PDLSCs) has recently been proposed for the development of new periodontal regenerative therapies. Although the use of autologous PDLSC transplantation eliminates the potential of a significant host immune response against the donor cells, it is often difficult to generate enough ...
Wada, N., Menicanin, D., Shi, S., Bartold, P., Gronthos, S.   +4 more
openaire   +4 more sources

Near Infrared Laser Photobiomodulation of Periodontal Ligament Stem Cells.

The Chinese journal of dental research, 2022
To determine the effect of different energy densities of near infrared diode lasers with wavelengths of 810 or 940 nm on the proliferation and survival of periodontal ligament derived stem cells (PDLSCs).After isolation and characterisation, PDLSCs were cultured in clear 96-well plates.
Mohammd Ayyoub, Rigi-Ladez, Seyedeh Sareh, Hendi, Alireza, Mirzaei, Leila, Gholami, Reza, Fekrazad   +4 more
openaire   +2 more sources

Recovery of Stem Cells from Cryopreserved Periodontal Ligament

Journal of Dental Research, 2005
Human post-natal stem cells possess a great potential to be utilized in stem-cell-mediated clinical therapies and tissue engineering. It is not known whether cryopreserved human tissues contain functional post-natal stem cells. In this study, we utilized human periodontal ligament to test the hypothesis that cryopreserved human periodontal ligament ...
B. SEO, MIURA, W. SONOYAMA, C. COPPE, STANYON, ROSCOE ROBERT, S. SHI   +5 more
openaire   +3 more sources

Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium

Stem Cells and Development, 2019
Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and protection of tooth, nerve, and blood vessels from injury by mechanical loading.
Atsushi, Tomokiyo, Naohisa, Wada, Hidefumi, Maeda   +2 more
openaire   +2 more sources