Results 251 to 260 of about 12,081 (284)

Periodontal ligament stem cells promote polarization of M2 macrophages

Journal of Leukocyte Biology, 2022
AbstractMacrophages are widely distributed in a variety of tissues, and the different state of macrophages polarization is closely related to the occurrence, development, and prognosis of inflammation, including periodontitis, a chronic inflammatory disease leading to tooth loss worldwide.
Jiani, Liu, Hong, Wang, Ludan, Zhang, Xiaoyu, Li, Xiaoling, Ding, Gang, Ding, Fulan, Wei   +6 more
openaire   +2 more sources

Periodontal ligament stem cells: an update and perspectives

Journal of Investigative and Clinical Dentistry, 2014
AbstractChronic periodontitis is a serious infectious and inflammatory oral disease of humans worldwide. Conventional treatment modalities are effective for controlling periodontal disease. However, the regeneration of damaged periodontal tissues remains a major challenge in clinical practice due to the complex structure of the periodontium.
Chamila Prageeth Pandula, PK, Zhang, C, Jin, L, Samaranayake, LP   +3 more
openaire   +4 more sources

Extracellular Matrix from Periodontal Ligament Cells Could Induce the Differentiation of Induced Pluripotent Stem Cells to Periodontal Ligament Stem Cell-Like Cells

Stem Cells and Development, 2018
The periodontal ligament (PDL) plays an important role in anchoring teeth in the bone socket. Damage to the PDL, such as after severe inflammation, can be treated with a therapeutic strategy that uses stem cells derived from PDL tissue (PDLSCs), a strategy that has received intense scrutiny over the past decade. However, there is an insufficient number
Sayuri, Hamano, Atsushi, Tomokiyo, Daigaku, Hasegawa, Shinichiro, Yoshida, Hideki, Sugii, Hiromi, Mitarai, Shoko, Fujino, Naohisa, Wada, Hidefumi, Maeda   +8 more
openaire   +2 more sources

Plasticity of Stem Cells Derived from Adult Periodontal Ligament

Regenerative Medicine, 2009
The neural crest contains pluripotent cells that can give rise to neurons and glial cells of the peripheral nervous system, endocrine cells, connective tissue cells, muscle cells and pigment cells during embryonic development. Stem cells derived from the neural crest may still reside in neural crest derivatives including the periodontal ligament (PDL).
C-Y Charles, Huang, Daniel, Pelaez, Juan, Dominguez-Bendala, Juan Dominguez, Bendala, Franklin, Garcia-Godoy, Herman S, Cheung   +5 more
openaire   +2 more sources

Location of putative stem cells in human periodontal ligament

Journal of Periodontal Research, 2006
Background and Objective:  The origin of cells in the mature periodontium, and the location of their progenitors, are still unknown. It is also unknown whether inflammation influences the number and distribution of these cells within the periodontium. Molecules such as STRO‐1, CD146 and CD44 have been identified on a variety of mesenchymal stem cells ...
Chen, S., Marino, V., Gronthos, S., Bartold, P.   +3 more
openaire   +3 more sources

Xeno-Free Culture of Human Periodontal Ligament Stem Cells

2014
The possibility of transplanting adult stem cells into damaged organs has opened a new prospective for the treatment of several human pathologies. Currently, in vitro expansion and culture of mesenchymal stem cells is founded on supplementing cell culture and differentiation medium with fetal calf serum (FCS) or fetal bovine serum (FBS) that contain ...
TRUBIANI, Oriana, DIOMEDE, FRANCESCA
openaire   +2 more sources

Periodontal Ligament Stem Cells Possess the Characteristics of Pericytes

Journal of Periodontology, 2013
Background: Periodontal ligament (PDL) contributes to maintaining homeostasis in periodontal tissues by supplying stem/progenitor cells. It has long been suggested that PDL stem cells/progenitors are located around blood vessels. Recently mesenchymal stem cells (MSCs) have been isolated and cultured from PDL in vitro, although the location of the stem ...
Kengo, Iwasaki, Motohiro, Komaki, Naoki, Yokoyama, Yuichi, Tanaka, Atsuko, Taki, Yasuyuki, Kimura, Masaki, Takeda, Shigeru, Oda, Yuichi, Izumi, Ikuo, Morita   +9 more
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Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration

Acta Biomaterialia, 2019
Mesenchymal stem cells (MSCs) are potential therapeutics for the treatment of periodontal defects. It is increasingly accepted that MSCs mediate tissue repair through secretion of trophic factors, particularly exosomes. Here, we investigated the therapeutic effects of human MSC exosome-loaded collagen sponge for regeneration of surgically created ...
Jacob Ren Jie, Chew, Shang Jiunn, Chuah, Kristeen Ye Wen, Teo, Shipin, Zhang, Ruenn Chai, Lai, Jia Hui, Fu, Lum Peng, Lim, Sai Kiang, Lim, Wei Seong, Toh   +8 more
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Non-coding RNAs Function in Periodontal Ligament Stem Cells

Stem Cell Reviews and Reports
Non-coding RNA has many types which has rich functions and plays an important role in the study of basic molecular mechanisms. Many non-coding RNA have important implications for pluripotent stem cells and embryonic stem cells. It has been found to affect the self-renewal and osteogenesis of many types of stem cells.
Wei Zhai, Jie Gao, Wen Qin, Yuerong Xu
openaire   +2 more sources

Human Embryonic Stem Cell Differentiation on Periodontal Ligament Fibroblasts

2009
Human embryonic stem cells' (hESCs) unlimited proliferative potential and differentiation capability to all somatic cell types made them potential cell source in different cell-based tissue engineering strategies as well as various experimental applications in fields such as developmental biology, pharmacokinetics, toxicology, and genetics. Periodontal
Y Murat, Elçin, Bülend, Inanç, A Eser, Elçin   +2 more
openaire   +2 more sources