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UCHL1 Impairs Periodontal Ligament Stem Cell Osteogenesis in Periodontitis

Journal of Dental Research, 2022
Periodontitis comprises a series of inflammatory responses resulting in alveolar bone loss. The suppression of osteogenesis of periodontal ligament stem cells (PDLSCs) by inflammation is responsible for impaired alveolar bone regeneration, which remains an ongoing challenge for periodontitis therapy.
L. Lin   +11 more
openaire   +2 more sources

Stem cell properties of human periodontal ligament cells

Journal of Periodontal Research, 2006
Background and Objective:  Stem cells have been used for regenerative therapies in various fields. The proportion of cells that possess stem cell properties in human periodontal ligament (PDL) cells is not yet well understood. In this study, we quantitatively characterized human PDL cells to clarify their stem cell properties, including self‐renewal ...
K, Nagatomo   +7 more
openaire   +2 more sources

Periodontal Ligament Stem Cells: An Overview

Journal of Oral Biosciences, 2010
Adult postnatal stem cells are multipotent and can be experimentally induced to differentiate into various specialized cell lineages. This has generated considerable interest in the arena of stem cell-based therapeutics. The identification of stem cells within the periodontal ligament represents a significant development in this regard.
Aneesha Acharya   +2 more
openaire   +1 more source

Periodontal Ligament Stem Cell Isolation Protocol: A Systematic Review

Current Stem Cell Research & Therapy, 2022
Abstract: Despite the plethora of literature regarding isolation and characterization of periodontal ligament stem cells (PDLSCs), due to the existence of controversies in the results, in this comprehensive review, we aimed to summarize and compare the effect of isolation methods on PDLSC properties, including clonogenicity, viability/proliferation ...
Maryam Rezai Rad   +3 more
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Characterization of Stem Cells from Alveolar Periodontal Ligament

Tissue Engineering Part A, 2011
Complete and predicable regeneration of complex periodontal structures, which include cementum, periodontal ligament (PDL), and alveolar bone, has been a great challenge for periodontal researchers. It is generally believed that human PDL from the root surface contains stem cells (r-PDLSCs), which can enhance cementum/PDL-like tissues regeneration in ...
Lei, Wang   +9 more
openaire   +2 more sources

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