Results 71 to 80 of about 3,061,254 (347)

Endovascular single-branched stent graft to treat complicated type B aortic dissection involving aortic arch anomalies

open access: yesEuropean Journal of Medical Research
Background The optimal treatment of complicated type B aortic dissection (cTBAD) involving arch anomalies remain unclear. Methods We consecutively enrolled patients with cTBAD involving arch anomalies who underwent endovascular repair using a single ...
Mengyang Kang   +5 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Communications Between Peripheral and the Brain-Resident Immune System in Neuronal Regeneration After Stroke

open access: yesFrontiers in Immunology, 2020
Cerebral ischemia may cause irreversible neural network damage and result in functional deficits. Targeting neuronal repair after stroke potentiates the formation of new connections, which can be translated into a better functional outcome.
Fangxi Liu   +9 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Open safety pin ingestion - Usual method of removal in an unusual way

open access: yesJournal of Digestive Endoscopy, 2013
Single foreign body ingestion is a common scenario that is commonly encountered by gastroenterologists. The symptoms tend to be nonspecific and most of the foreign bodies pass spontaneously. Ingestion of sharp foreign bodies is also not uncommon.
Sathya G.   +3 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Prevalence, types, clinical associations, and determinants of peripheral neuropathy in rheumatoid patients

open access: yesAnnals of Indian Academy of Neurology, 2011
Background: Rheumatoid arthritis is a multi-system autoimmune disorder predominantly involving multiple small and large joints along with certain extra-articular manifestations.
Monodeep Biswas   +5 more
doaj   +1 more source

Peripheral urbanization: Autoconstruction, transversal logics, and politics in cities of the global south

open access: yes, 2017
Many cities around the world have been largely constructed by their residents, who build not only their own houses, but also frequently their neighborhoods.
Teresa P. R. Caldeira
semanticscholar   +1 more source

A Wireless Closed Loop System for Optogenetic Peripheral Neuromodulation

open access: yesNature, 2018
The fast-growing field of bioelectronic medicine aims to develop engineered systems that can relieve clinical conditions by stimulating the peripheral nervous system1–5.
A. Mickle   +24 more
semanticscholar   +1 more source

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