Results 51 to 60 of about 2,308,082 (355)

Blood biomarkers of peripheral neuropathy

Acta Neurologica Scandinavica, 2022
Traditionally, neurophysiology is the primary diagnostic and prognostic biomarker in peripheral neuropathy clinical practice; however, it may lack responsiveness in the context of slowly progressive neuropathies and where there is significant axonal damage.
Alexander M. Rossor, Mary M. Reilly
openaire   +2 more sources

Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis [PDF]

, 2015
Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is ...
Agnoli, C, Ashworth, A, Baglietto, L, Chadeau, M, Curry, E, Flanagan, JM, Flower, K, Frasca, G, Garcia-Closas, M, Jones, M, Krogh, V, Lund, E, Masala, G, Mattiello, A, Orr, N, Palli, D, Panico, S, Polidoro, S, Sacerdote, C, Sandanger, T, Severi, G, Swerdlow, A, Tomczyk, K, Tumino, R, van veldhoven, K, vineis, P   +25 more
core   +5 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Optimization of peripheral blood volume for in silico reconstitution of the human B‐cell receptor repertoire

FEBS Open Bio, 2022
B cells recognize antigens via membrane‐expressed B‐cell receptors (BCR) and antibodies. Similar human BCR sequences are frequently found at a significantly higher frequency than that theoretically calculated.
Hyunho Lee, Duck Kyun Yoo, Jerome Han, Ki Hyun Kim, Jinsung Noh, Yonghee Lee, Eunjae Lee, Sunghoon Kwon, Junho Chung   +8 more
doaj   +1 more source

Divergent Cytokine and Chemokine Responses at Early Acute Simian Immunodeficiency Virus Infection Correlated with Virus Replication and CD4 T Cell Loss in a Rhesus Macaque Model

Vaccines, 2023
Cytokine and chemokine levels remain one of the significant predictive factors of HIV pathogenesis and disease outcome. Understanding the impact of cytokines and chemokines during early acute infection will help to recognize critical changes during HIV ...
Nongthombam Boby, Apurv Srivastav, Sudesh K. Srivastav, Bapi Pahar   +3 more
doaj   +1 more source

Haemophagocytosis in the peripheral blood [PDF]

British Journal of Haematology, 1999
link_to_subscribed_fulltext
Au, WY, Kwong, YL
openaire   +4 more sources

An epidemiologic study of early biologic effects of benzene in Chinese workers. [PDF]

, 1996
Benzene is a recognized hematotoxin and leukemogen, but its mechanisms of action in humans are still uncertain. To provide insight into these processes, we carried out a cross-sectional study of 44 healthy workers currently exposed to benzene (median 8 ...
Bechtold, WE, Campleman, S, Dosemeci, M, Haas, R, Hayes, RB, Irons, RD, Kolachana, P, Li, GL, Linet, M, Lu, W, Meyer, KB, Quintana, PJ, Rothman, N, Smith, MT, Stillman, WS, Titenko-Holland, N, Wang, YZ, Wiemels, J, Xi, LQ, Yin, S, Zhang, L   +20 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Dose dependence of the intensity of free radical processes in the peripheral blood of conditionally healthy donors

Ядерна фізика та енергетика, 2019
The nature of the dependence of the intensity of free radical processes in the peripheral blood of donors on the dose of radiation in vitro (0.5 - 3.0 Gy) related to the parameters of the prooxidant-antioxidant ratio (PAR) and the content of malonic ...
L. I. Makovetska, E. A. Domina, M. O. Druzhуna, O. V. Muliarchuk   +3 more
doaj   +1 more source

A Preliminary Study on the Prognostic Impact of Neutrophil to Lymphocyte Ratio of the Bronchoalveolar Lavage Fluid in Patients with Lung Cancer

Diagnostics, 2021
The cumulative results indicate that the neutrophil to lymphocyte ratio of peripheral blood (pbNLR) is a useful prognostic factor in patients with various cancers.
Woo Kyung Ryu, Yeonsook Moon, Mi Hwa Park, Jun Hyeok Lim, Young Sam Kim, Kyung-Hee Lee, Seung Min Kwak, Changhwan Kim, Hae-Seong Nam   +8 more
doaj   +1 more source