Results 21 to 30 of about 4,841,252 (345)

γ-H2AX foci as in vivo effect biomarker in children emphasize the importance to minimize x-ray doses in paediatric CT imaging [PDF]

, 2014
Objectives: Investigation of DNA damage induced by CT x-rays in paediatric patients versus patient dose in a multicentre setting. Methods: From 51 paediatric patients (median age, 3.8 years) who underwent an abdomen or chest CT examination in one of the
A. De Backer, C. Ernst, C. Franck, C. Vandevoorde, H. Thierens, K. Bacher, K. Van De Moortele, L. Breysem, M. H. Smet, P. Smeets   +9 more
core   +2 more sources

Measuring dose in lung identifies peripheral tumour dose inaccuracy in SBRT audit

Physica Medica, 2023
Stereotactic Body Radiotherapy (SBRT) for lung tumours has become a mainstay of clinical practice worldwide. Measurements in anthropomorphic phantoms enable verification of patient dose in clinically realistic scenarios. Correction factors for reporting dose to the tissue equivalent materials in a lung phantom are presented in the context of a national
Maddison Shaw, Jessica Lye, Andrew Alves, Joerg Lehmann, Masoumeh Sanagou, Moshi Geso, Rhonda Brown   +6 more
openaire   +2 more sources

Peripheral doses in patients undergoing Cyberknife treatment for intracranial lesions. A single centre experience

Radiation Oncology, 2011
Background Stereotactic radiosurgery/radiotherapy procedures are known to deliver a very high dose per fraction, and thus, the corresponding peripheral dose could be a limiting factor for the long term surviving patients.
Vlachopoulou Vassiliki, Antypas Christos, Delis Harry, Tzouras Argyrios, Salvaras Nikolaos, Kardamakis Dimitrios, Panayiotakis George   +6 more
doaj   +1 more source

Radioprotective Effect of Two Kinds of Protein Peptides in Ray-irradiated Mice

Shipin gongye ke-ji, 2022
Objective: To investigate the radioprotective effect of jackfruit protein peptide and collagen peptide with pleasant mouthfeel in many bioactive peptides in 60Co γ ray-irradiated mice.
Aiqing LIU, Haiyan WANG, Yingqiang WANG, Zheng YAN, Zhiguo LI, Zhimin XU   +5 more
doaj   +1 more source

Randomized double-blind, placebo-controlled study of oral gabapentin for prevention of neuropathy in patients receiving paclitaxel

Trials, 2023
Background Peripheral neuropathy is a common dose-limiting side effect of paclitaxel. To date, there is no effective strategy to prevent paclitaxel-induced peripheral neuropathy.
Praful Pandey, Akash Kumar, Deepam Pushpam, Sachin Khurana, Prabhat Singh Malik, Ajay Gogia, Elavarasi Arunmozhimaran, Mamta Bhushan Singh, Dinu Santha Chandran, Atul Batra   +9 more
doaj   +1 more source

Patient-Specific Fetal Dose Determination for Multi-Target Gamma Knife Radiosurgery: Computational Model and Case Report. [PDF]

, 2017
A 42-year-old woman at 29 weeks gestation via in vitro fertilization who presented with eight metastatic brain lesions received Gamma Knife stereotactic radiosurgery (GKSRS) at our institution. In this study, we report our clinical experience and a ...
Braunstein, Steve, Ma, Lijun, McDermott, Michael, Paulsson, Anna K, Phillips, Justin, Sneed, Patricia K, Theodosopoulos, Philip V   +6 more
core   +1 more source

A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours [PDF]

, 2016
Purpose: We performed a multi-centre phase I study to assess the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of the orally available small molecule mitogen-activated protein kinase kinase (MEK) 1/2 inhibitor, WX-554, and to determine the ...
Allen, Rodger, Anthoney, Alan, Banerji, Udai, Bevan, Paul, Boddy, Alan V., Buerkle, Markus, Coyle, Vicky, Cresti, Nicola, Dean, Emma, Drew, Yvette, Evans, T.R. Jefferey, Greystoke, Alastair, Griffin, Melanie J., Jamieson, David, Mala, Carola, Merriman, Mark, Plummer, Ruth, Ranson, Malcolm, Rodgers, Lisa, Sludden, Julieann, Swales, Karen, Wilson, Richard H.   +21 more
core   +2 more sources

Respiration-Induced Intraorgan Deformation of the Liver: Implications for Treatment Planning in Patients Treated With Fiducial Tracking. [PDF]

, 2017
Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation
Anwar, Mekhail, Chang, Albert J, Descovich, Martina, Gottschalk, Alexander R, Paulsson, Anna K, Pinnaduwage, Dilini, Sudhyadhom, Atchar, Yom, Sue S   +7 more
core   +1 more source

Peripheral dose measurements in cervical cancer radiotherapy: a comparison of volumetric modulated arc therapy and step-and-shoot IMRT techniques

Radiation Oncology, 2014
PurposeThe aim of this study was to investigate the peripheral doses resulting from volumetric modulated arc therapy (VMAT) and intensity modulated radiotherapy (IMRT) techniques in cervical cancer radiotherapy.MethodsNine patients with cervical cancer ...
M. Jia, Xu Zhang, C. Yin, Ge Feng, Na Li, Song Gao, Da W Liu   +6 more
semanticscholar   +1 more source

Lung Locations Most Affected by Dose-Calculation Algorithms in CyberKnife Stereotactic Body Radiotherapy

IEEE Access, 2019
CyberKnife is a robotic stereotactic body radiotherapy (SBRT) system that precisely delivers large radiation doses to a target. Tissue heterogeneity and shape can be problems.
Yu-Jie Huang, Chih-Hsueh Lin, Hsiao-Han Chang, Hui-Min Ting, Pei-Ju Chao, I-Hsing Tsai, Chao-Hong Liu, Chun-Chieh Huang, Tsair-Fwu Lee   +8 more
doaj   +1 more source