Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases
ABSTRACT Previously regarded merely as a potentially harmful waste product of heme catabolism, bilirubin has now emerged as a pleiotropic molecule with potent antioxidant, anti‐inflammatory, and hormone‐like properties. Recent findings have revealed protective effects against cardiovascular, metabolic, autoimmune, and neoplastic diseases, as well as ...
Sri Jayanti +3 more
wiley +1 more source
Aging and Peripheral Nerve Injuries: Impaired Repair, Inflammaging Impact, and Regeneration Resistance. [PDF]
Gu X +7 more
europepmc +1 more source
Traumatic peripheral nerve injuries: a classification proposal. [PDF]
Lavorato A +10 more
europepmc +1 more source
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Regenerative medicine approaches for the treatment of peripheral nerve injuries: progress and challenges. [PDF]
Yang H, Bao Q, Gu X, Cong M.
europepmc +1 more source
Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang +8 more
wiley +1 more source
Surgical Outcomes in Non-Transected and Partially Transected Peripheral Nerve Injuries. [PDF]
Sakthiyendran NA +5 more
europepmc +1 more source
Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries. [PDF]
Zhang M +7 more
europepmc +1 more source

