Results 161 to 170 of about 118,069 (298)

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Comparative surgical outcomes in ballistic peripheral nerve injuries: A single-surgeon experience and mechanism-based classification of gunshot versus shrapnel trauma. [PDF]

Brain Spine
Rochkind S.
europepmc   +1 more source

Decellularized Graft for Repairing Severe Peripheral Nerve Injuries in Sheep. [PDF]

Neurosurgery, 2023
Contreras E, Traserra S, Bolívar S, Nieto-Nicolau N, Jaramillo J, Forés J, Jose-Cunilleras E, Moll X, García F, Delgado-Martínez I, Fariñas O, López-Chicón P, Vilarrodona A, Udina E, Navarro X, Navarro X.   +15 more
europepmc   +1 more source

Endocrinology of the hypothalamus and the pituitary gland [PDF]

, 1973
Kuhlendahl, Hans, Scriba, Peter Christian   +1 more
core   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Translation and validation of the Swedish version of the problematic experience of therapy scale (PETS-Swe) for patients with peripheral nerve injuries in the hand. [PDF]

Hand Ther
Wijk U, Larsson SL, Svingen J.
europepmc   +1 more source

Regenerative Strategies in Treatment of Peripheral Nerve Injuries in Different Animal Models. [PDF]

Tissue Eng Regen Med, 2023
Khaled MM, Ibrahium AM, Abdelgalil AI, El-Saied MA, El-Bably SH.   +4 more
europepmc   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Direct Cost and Incidence of Surgically Treated Upper-Extremity Peripheral Nerve Injuries in the United States. [PDF]

J Hand Surg Am
Randall ZD, Keller MR, Morris MT, Brogan DM, Dy CJ.   +4 more
europepmc   +1 more source

Molecular Basis of Surgical Coaptation Techniques in Peripheral Nerve Injuries. [PDF]

J Clin Med, 2023
Pereira CT, Hill EE, Stasyuk A, Parikh N, Dhillon J, Wang A, Li A.   +6 more
europepmc   +1 more source