Results 231 to 240 of about 120,257 (337)

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Cyclooxygenase-1 in the Spinal Cord Is Altered after Peripheral Nerve Injury [PDF]

, 2003
Xiaoying Zhu, James C. Eisenach
openalex   +1 more source

Compound muscle action potential amplitude predicts the severity of cubital tunnel syndrome [PDF]

, 2019
El-Haj, Madi, Mackinnon, Susan E, Moore, Amy M, Patterson, Megan M, Power, Hollie A, Sharma, Ketan   +5 more
core   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Case Series of Traumatic Peripheral Nerve Injuries in Pediatric Patients Treated with Allograft Repair. [PDF]

J Hand Surg Glob Online
Van Gheem J, Rounds A, Blackwood T, Cox C, Hernandez EJ, McKee D, MacKay B.   +6 more
europepmc   +1 more source

Peripheral Nerve Injuries During Cardiac Surgery: Risk Factors, Diagnosis, Prognosis, and Prevention

, 2000
Ajeet D. Sharma, C. Lee Parmley, Gautam Sreeram, Hilary P. Grocott   +3 more
openalex   +1 more source

An uncommon peripheral nerve injury after penetrating injury of the forearm: the importance of clinical examination [PDF]

, 2003
D Sunderamoorthy
openalex   +1 more source

H/M-ratio in spasticity before and after therapy with vibration impulses [PDF]

, 1988
Krause, Klaus-Henning, Kummer, R. von, Morche, K.   +2 more
core  

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

Epidemiology and regional variance of traumatic peripheral nerve injuries in Sweden: A 15-year observational study. [PDF]

PLoS One
Magnéli M, Axenhus M.
europepmc   +1 more source