Therapeutic Low-Intensity Ultrasound for Peripheral Nerve Regeneration – A Schwann Cell Perspective
Frontiers in Cellular Neuroscience, 2022 Peripheral nerve injuries are common conditions that can arise from trauma (e.g., compression, severance) and can lead to neuropathic pain as well as motor and sensory deficits.
Jenica Acheta +3 more
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MicroRNAs modulate schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes [PDF]
, 2011 In the peripheral nervous system, Schwann cells (SCs) surrounding damaged axons undergo an injury response that is driven by an intricate transcriptional program and is critical for nerve regeneration.
Chang, Li-Wei +4 more
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The role of exercise on peripheral nerve regeneration: from animal model to clinical application
Heliyon, 2021 Peripheral nerve injury is a complex condition with a variety of signs and symptoms depending on the severity and nerves involved. Peripheral nerve damage may lead to sensory and motor functions deficits and even lifelong disability, causing important ...
Grazia Maugeri +7 more
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Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infra-orbital blood-nerve barrier following chronic constriction injury? [PDF]
, 2017 BackgroundBlood–nerve barrier disruption is pivotal in the development of neuroinflammation, peripheral sensitization, and neuropathic pain after peripheral nerve injury.
Boucher, Yves +7 more
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Development of a core outcome set for traumatic brachial plexus injuries (COMBINE): study protocol
BMJ Open, 2019 IntroductionTraumatic brachial plexus injury (TBPI) involves major trauma to the large nerves of the arm which control the movement and sensation. Fifty per cent of injuries result in complete paralysis of the arm with many other individuals having ...
Christina Jerosch-Herold +3 more
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Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury [PDF]
, 2015 The goal of this surgical protocol is to expose the facial nerve, which innervates the facial musculature, at its exit from the stylomastoid foramen and either cut or crush it to induce peripheral nerve injury.
Batka, Richard J. +5 more
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Role of Netrin-1 Signaling in Nerve Regeneration. [PDF]
, 2017 Netrin-1 was the first axon guidance molecule to be discovered in vertebrates and has a strong chemotropic function for axonal guidance, cell migration, morphogenesis and angiogenesis.
Cajal +11 more
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Scientific Reports, 2023 Sigma-1 Receptor has been shown to localize to sites of peripheral nerve injury and back pain. Radioligand probes have been developed to localize Sigma-1 Receptor and thus image pain source.
Ethan Schonfeld +6 more
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The glia response after peripheral nerve injury: A comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies [PDF]
, 2017 The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). One reason for this difference is the difference in glial cell types between the two systems.
Barton, Matthew J. +4 more
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Lumbosacral Plexogram: An Aid to Reconstructive Nerve Possibilities in the Lower Extremity
Plastic and Reconstructive Surgery, Global OpenSummary:. The lumbosacral plexus is the network of nerves responsible for the motor and sensory function of the pelvis and lower limb. Our observation is that the anatomy of this plexus is less familiar to surgeons than that of the brachial plexus ...
Sami Ramadan, FRCS(Plast) +5 more
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