Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. [PDF]
, 2020 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Basbaum, Allan I +8 more
core +1 more source
Lumbosacral Plexogram: An Aid to Reconstructive Nerve Possibilities in the Lower Extremity
Plastic and Reconstructive Surgery, Global OpenSummary:. The lumbosacral plexus is the network of nerves responsible for the motor and sensory function of the pelvis and lower limb. Our observation is that the anatomy of this plexus is less familiar to surgeons than that of the brachial plexus ...
Sami Ramadan, FRCS(Plast) +5 more
doaj +1 more source
Distinct VIP and PACAP Functions in the Distal Nerve Stump During Peripheral Nerve Regeneration [PDF]
, 2019 Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylyl Cyclase Activating Peptide (PACAP) are regeneration-associated neuropeptides, which are up-regulated by neurons following peripheral nerve injury.
Dun, Xin Peng +5 more
core +2 more sources
Tissue engineering for the repair of peripheral nerve injury
Neural Regeneration Research, 2019 Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering.
Pei-Xun Zhang +7 more
doaj +1 more source
The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration
Frontiers in Bioengineering and Biotechnology, 2022 Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang +7 more
doaj +1 more source
Peripheral Nerve Injury Induces Dynamic Changes of Tight Junction Components
Frontiers in Physiology, 2018 Tight junctions seal off physical barriers, regulate fluid and solute flow, and protect the endoneurial microenvironment of the peripheral nervous system. Physical barriers in the peripheral nervous system were disrupted after nerve injury.
Xinghui Wang +8 more
doaj +1 more source
Plasticity of the Central Nervous System Involving Peripheral Nerve Transfer
Neural Plasticity, 2022 Peripheral nerve injury can lead to partial or complete loss of limb function, and nerve transfer is an effective surgical salvage for patients with these injuries.
Jun Shen
doaj +1 more source
Starting A Peripheral Nerve Surgery Unit in an Area of Limited Resources - Our Experience [PDF]
, 2018 Dedicated peripheral nerve surgery centers are few in developing countries where majority of affected patients either remain untreated or are simply palliated with just physiotherapy.
Onyia, Chiazor U. +2 more
core +1 more source
Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury [PDF]
, 2015 The goal of this surgical protocol is to expose the facial nerve, which innervates the facial musculature, at its exit from the stylomastoid foramen and either cut or crush it to induce peripheral nerve injury.
Batka, Richard J. +5 more
core +1 more source
Mesenchymal Stem Cell Treatment Perspectives in Peripheral Nerve Regeneration: Systematic Review [PDF]
, 2021 Traumatic peripheral nerve lesions affect hundreds of thousands of patients every year; their consequences are life-altering and often devastating and cause alterations in movement and sensitivity.
Boido, Marina Maria +11 more
core +1 more source