Results 21 to 30 of about 164,391 (268)

Distal Nerve Transfer for Opponensplasty in the Setting of High Median Nerve Injury: A Case Series

Advances in Orthopedics
Conclusion: In high median-nerve injury, early reconstructive intervention can prevent the thenar muscle atrophy and leads to prompt reinnervation and complete restoration of thenar function.
Mohammadreza Emamhadi, Mohammad Haghani Dogahe, Amirreza Emamhadi   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Surgical Approach to a Medial Epicondylectomy in Cubital Tunnel Syndrome

Plastic and Reconstructive Surgery, Global Open
Summary:. Cubital tunnel syndrome, a common neuropathy of the upper limb, presents with sensory and motor symptoms, impacting hand function and grip strength.
Abdus S. Burahee, MBChB, Liron S. Duraku, PhD, Rajive Jose, MD, Michiel J. Zuidam, PhD, Dominic M. Power, MB, BChir   +4 more
doaj   +1 more source

Peripheral Nerve Injury Induces Dynamic Changes of Tight Junction Components

Frontiers in Physiology, 2018
Tight junctions seal off physical barriers, regulate fluid and solute flow, and protect the endoneurial microenvironment of the peripheral nervous system. Physical barriers in the peripheral nervous system were disrupted after nerve injury.
Xinghui Wang, Yang Miao, Jun Ni, Yaxian Wang, Tianmei Qian, Jun Yu, Qianyan Liu, Pan Wang, Sheng Yi   +8 more
doaj   +1 more source

The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration

Frontiers in Bioengineering and Biotechnology, 2022
Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang, Yuhui Jiang, Xiaoxuan Tang, Xiaoxuan Tang, Tao Li, Jue Ling, Yumin Yang, Yumin Yang   +7 more
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Inhibition of CD44 suppresses the formation of fibrotic scar after spinal cord injury via the JAK2/STAT3 signaling pathway

iScience
Summary: Fibrotic scar is one of the main impediments to axon regeneration following spinal cord injury (SCI). In this study, we found that CD44 was upregulated during the formation of fibrotic scar, and blocking CD44 by IM7 caused downregulation of ...
Jin Guo, Tuo Yang, Weizhong Zhang, Kaiming Yu, Xiong Xu, Weizhen Li, Lili Song, Xiaosong Gu, Rangjuan Cao, Shusen Cui   +9 more
doaj   +1 more source

Roles of neural stem cells in the repair of peripheral nerve injury

Neural Regeneration Research, 2017
Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair.
Chong Wang, Chang-feng Lu, Jiang Peng, Cheng-dong Hu, Yu Wang   +4 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Plasticity of the Central Nervous System Involving Peripheral Nerve Transfer

Neural Plasticity, 2022
Peripheral nerve injury can lead to partial or complete loss of limb function, and nerve transfer is an effective surgical salvage for patients with these injuries.
Jun Shen
doaj   +1 more source