Results 31 to 40 of about 286,657 (266)

Apoptotic gene expression in neuropathic pain [PDF]

open access: yes, 2008
Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi   +6 more
core   +2 more sources

Development of affinity-based delivery of NGF from a chondroitin sulfate biomaterial. [PDF]

open access: yes, 2011
Chondroitin sulfate is a major component of the extracellular matrix in both the central and peripheral nervous systems. Chondroitin sulfate is upregulated at injury, thus methods to promote neurite extension through chondroitin sulfate-rich matrices and
Butterfield, Karen Chao   +2 more
core   +1 more source

Effect of melatonin supplemented at the light or dark period on recovery of sciatic nerve injury in rats [PDF]

open access: yes, 2017
Peripheral nerve injuries can cause disabilities, social or economic problems. Melatonin, the secretory product of the pineal gland has antioxidant and anti-inflammatory actions.
Amin, Shaimaa Nasr   +4 more
core   +1 more source

Tissue engineering for the repair of peripheral nerve injury

open access: yesNeural Regeneration Research, 2019
Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering.
Pei-Xun Zhang   +7 more
doaj   +1 more source

Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA [PDF]

open access: yes, 2017
Precise regulation of Egr2 transcription is fundamentally important to the control of peripheral myelination. Here, we describe a long non-coding RNA antisense to the promoter of Egr2 (Egr2-AS-RNA).
Langer, Robert S   +6 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Distal Nerve Transfer for Opponensplasty in the Setting of High Median Nerve Injury: A Case Series

open access: yesAdvances in Orthopedics
Conclusion: In high median-nerve injury, early reconstructive intervention can prevent the thenar muscle atrophy and leads to prompt reinnervation and complete restoration of thenar function.
Mohammadreza Emamhadi   +2 more
doaj   +1 more source

The success of biomaterial-based tissue engineering strategies for peripheral nerve regeneration

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Peripheral nerve injury is a clinically common injury that causes sensory dysfunction and locomotor system degeneration, which seriously affects the quality of the patients’ daily life.
Yuhui Jiang   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Surgical Approach to a Medial Epicondylectomy in Cubital Tunnel Syndrome

open access: yesPlastic and Reconstructive Surgery, Global Open
Summary:. Cubital tunnel syndrome, a common neuropathy of the upper limb, presents with sensory and motor symptoms, impacting hand function and grip strength.
Abdus S. Burahee, MBChB   +4 more
doaj   +1 more source

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