Results 11 to 20 of about 164,391 (268)

Nerve Suture Combined With ADSCs Injection Under Real-Time and Dynamic NIR-II Fluorescence Imaging in Peripheral Nerve Regeneration in vivo

Frontiers in Chemistry, 2021
Peripheral nerve injury gives rise to devastating conditions including neural dysfunction, unbearable pain and even paralysis. The therapeutic effect of current treatment for peripheral nerve injury is unsatisfactory, resulting in slow nerve regeneration
Shixian Dong, Sijia Feng, Yuzhou Chen, Mo Chen, Yimeng Yang, Jian Zhang, Huizhu Li, Xiaotong Li, Liang Ji, Xing Yang, Yuefeng Hao, Jun Chen, Yan Wo   +12 more
doaj   +1 more source

Therapeutic Low-Intensity Ultrasound for Peripheral Nerve Regeneration – A Schwann Cell Perspective

Frontiers in Cellular Neuroscience, 2022
Peripheral nerve injuries are common conditions that can arise from trauma (e.g., compression, severance) and can lead to neuropathic pain as well as motor and sensory deficits.
Jenica Acheta, Shannon B. Z. Stephens, Sophie Belin, Yannick Poitelon   +3 more
doaj   +1 more source

The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves

Frontiers in Cellular Neuroscience, 2019
Peripheral Nerve Injury (PNI) is common following blunt or penetrating trauma with an estimated prevalence of 2% among the trauma population. The resulting economic and societal impacts are significant.
Matthew Wilcox, Matthew Wilcox, Matthew Wilcox, Tom J. Quick, Tom J. Quick, Tom J. Quick, James B. Phillips, James B. Phillips   +7 more
doaj   +1 more source

The role of exercise on peripheral nerve regeneration: from animal model to clinical application

Heliyon, 2021
Peripheral nerve injury is a complex condition with a variety of signs and symptoms depending on the severity and nerves involved. Peripheral nerve damage may lead to sensory and motor functions deficits and even lifelong disability, causing important ...
Grazia Maugeri, Velia D'Agata, Bruno Trovato, Federico Roggio, Alessandro Castorina, Michele Vecchio, Michelino Di Rosa, Giuseppe Musumeci   +7 more
doaj   +1 more source

Mechanisms Underlying Clinical Efficacy of Angiotensin II Type 2 Receptor (ATR) Antagonist EMA401 in Neuropathic Pain: Clinical Tissue and in Vitro Studies

Molecular Pain, 2015
Background The clinical efficacy of the Angiotensin II (AngII) receptor AT 2 R antagonist EMA401, a novel peripherallyrestricted analgesic, was reported recently in post-herpetic neuralgia.
Uma Anand, Yiangos Yiangou, Marco Sinisi, Michael Fox, Anthony MacQuillan, Tom Quick, Yuri E Korchev, Chas Bountra, Tom McCarthy, Praveen Anand   +9 more
doaj   +1 more source

Development of a core outcome set for traumatic brachial plexus injuries (COMBINE): study protocol

BMJ Open, 2019
IntroductionTraumatic brachial plexus injury (TBPI) involves major trauma to the large nerves of the arm which control the movement and sensation. Fifty per cent of injuries result in complete paralysis of the arm with many other individuals having ...
Christina Jerosch-Herold, Caroline Miller, Jane Cross, Dominic M Power   +3 more
doaj   +1 more source

Lumbosacral Plexogram: An Aid to Reconstructive Nerve Possibilities in the Lower Extremity

Plastic and Reconstructive Surgery, Global Open
Summary:. The lumbosacral plexus is the network of nerves responsible for the motor and sensory function of the pelvis and lower limb. Our observation is that the anatomy of this plexus is less familiar to surgeons than that of the brachial plexus ...
Sami Ramadan, FRCS(Plast), Catherine Leng, MRCS, Liron S. Duraku, MD, PhD, Tahseen Chaudhry, FRCS(Tr&Orth), Dominic M. Power, FRCS(Tr&Orth), Samuel George, FRCS(Plast)   +5 more
doaj   +1 more source

Sigma-1 receptor expression in a subpopulation of lumbar spinal cord microglia in response to peripheral nerve injury

Scientific Reports, 2023
Sigma-1 Receptor has been shown to localize to sites of peripheral nerve injury and back pain. Radioligand probes have been developed to localize Sigma-1 Receptor and thus image pain source.
Ethan Schonfeld, Thomas Michael Johnstone, Ghani Haider, Aaryan Shah, Neelan Joseph Marianayagam, Sandip Biswal, Anand Veeravagu   +6 more
doaj   +1 more source

Tissue engineering for the repair of peripheral nerve injury

Neural Regeneration Research, 2019
Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering.
Pei-Xun Zhang, Na Han, Yu-Hui Kou, Qing-Tang Zhu, Xiao-Lin Liu, Da-Ping Quan, Jian-Guo Chen, Bao-Guo Jiang   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source