Results 11 to 20 of about 1,905,670 (289)

An organized 3D in vitro model for peripheral nerve studies [PDF]

open access: yes, 2013
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
core   +6 more sources

Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]

open access: yes, 2003
The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Todd, A.J.   +3 more
core   +9 more sources

Expression of neuropeptides – galanin and Reg2 - in subcategories of nociceptors after nerve injury [PDF]

open access: yes, 2010
PhDNeuropeptides show dynamic changes in expression after nerve injury, and have been implicated in chronic pain states. I sought to compare expression of two peptides which are upregulated after nerve injury, galanin and Reg2, and to determine the ...
Burrows, Karen Lynne
core   +4 more sources

Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]

open access: yes, 2012
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo   +24 more
core   +2 more sources

Nerve Suture Combined With ADSCs Injection Under Real-Time and Dynamic NIR-II Fluorescence Imaging in Peripheral Nerve Regeneration in vivo

open access: yesFrontiers in Chemistry, 2021
Peripheral nerve injury gives rise to devastating conditions including neural dysfunction, unbearable pain and even paralysis. The therapeutic effect of current treatment for peripheral nerve injury is unsatisfactory, resulting in slow nerve regeneration
Shixian Dong   +12 more
doaj   +1 more source

Functional and immunological peculiarities of peripheral nerve allografts

open access: yesNeural Regeneration Research, 2022
This review addresses the accumulating evidence that live (not decellularized) allogeneic peripheral nerves are functionally and immunologically peculiar in comparison with many other transplanted allogeneic tissues.
Kelly C.S. Roballo   +4 more
doaj   +1 more source

The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves

open access: yesFrontiers in Cellular Neuroscience, 2019
Peripheral Nerve Injury (PNI) is common following blunt or penetrating trauma with an estimated prevalence of 2% among the trauma population. The resulting economic and societal impacts are significant.
Matthew Wilcox   +7 more
doaj   +1 more source

Therapeutic Low-Intensity Ultrasound for Peripheral Nerve Regeneration – A Schwann Cell Perspective

open access: yesFrontiers in Cellular Neuroscience, 2022
Peripheral nerve injuries are common conditions that can arise from trauma (e.g., compression, severance) and can lead to neuropathic pain as well as motor and sensory deficits.
Jenica Acheta   +3 more
doaj   +1 more source

Mechanisms Underlying Clinical Efficacy of Angiotensin II Type 2 Receptor (ATR) Antagonist EMA401 in Neuropathic Pain: Clinical Tissue and in Vitro Studies

open access: yesMolecular Pain, 2015
Background The clinical efficacy of the Angiotensin II (AngII) receptor AT 2 R antagonist EMA401, a novel peripherallyrestricted analgesic, was reported recently in post-herpetic neuralgia.
Uma Anand   +9 more
doaj   +1 more source

Development of a core outcome set for traumatic brachial plexus injuries (COMBINE): study protocol

open access: yesBMJ Open, 2019
IntroductionTraumatic brachial plexus injury (TBPI) involves major trauma to the large nerves of the arm which control the movement and sensation. Fifty per cent of injuries result in complete paralysis of the arm with many other individuals having ...
Christina Jerosch-Herold   +3 more
doaj   +1 more source

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