Results 21 to 30 of about 670,710 (262)

Differences in sensitivity to mTHPC-mediated photodynamic therapy of neurons, glial cells and MCF7 cells in a 3-dimensional cell culture model [PDF]

open access: yes, 2008
The effect of photodynamic therapy (PDT) on the cells of the nervous system is an important consideration in the treatment of tumours that are located within or adjacent to the brain, spinal cord and peripheral nerves.
MacRobert, A. J.   +2 more
core  

CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems [PDF]

open access: yes, 2019
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Amani Wehbi   +7 more
core   +2 more sources

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Midline1 and the development of the cranial peripheral nervous system [PDF]

open access: yes, 2008
Genetic abnormalities involving the skull and facial region account for around 1/3 of birth defects. Opitz BBB/G syndrome is one such disorder that gives rise to craniofacial malformations, as well as midline defects that cause gastrointestinal ...
Golding, Jon   +2 more
core  

Printable microscale interfaces for long-term peripheral nerve mapping and precision control [PDF]

open access: yes, 2019
The nascent field of bioelectronic medicine seeks to decode and modulate peripheral nervous system signals to obtain therapeutic control of targeted end organs and effectors.
Alice E. White   +11 more
core   +1 more source

Vasculitis and the peripheral nervous system [PDF]

open access: yesRheumatology, 2020
Abstract Peripheral neuropathy is a common feature of systemic vasculitis and can also occur when vessel wall inflammation is confined to the vasa nervorum, as a tissue-specific condition—non-systemic vasculitic neuropathy (NSVN). Typically, the clinical picture in both systemic and non-systemic cases is of a lower limb predominant ...
openaire   +3 more sources

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Peripheral Nervous System [PDF]

open access: yes, 2019
This study guide is intended for the students of medical higher educational institutions of IV accreditation level who study Human Anatomy in the English ...
Prykhodko, Olha Oleksiivna   +9 more
core  

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]

open access: yes, 2015
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky   +6 more
core   +2 more sources

AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training program

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye   +16 more
wiley   +1 more source

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