Results 51 to 60 of about 783,564 (214)

Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer\u27s Disease-Related Changes Through the Regulation of the Peripheral Immune System. [PDF]

, 2018
Alzheimer\u27s disease (AD) is a chronic progressive neurodegenerative disease. Its mechanism is still not clear. Majority of research focused on the central nervous system (CNS) changes, while few studies emphasize on peripheral immune system modulation.
Chai, Zhi, Chumber, Jasleen, Gao, Ye, Gu, Qingfang, Jiang, Yuqiang, Kumar, Gajendra, Liu, Chunyun, Ma, Cun-Gen, Xiao, Bao-Guo, Yan, Yuqing, Yu, Hongqiang, Yu, Jiezhong, Zhang, Guang-Xian, Zhang, Han-Ting, Zhao, Yijin   +14 more
core   +1 more source

Peripheral nervous system in limited systemic sclerosis

Reumatismo, 2011
Objectives. PNS is involved in Systemic Sclerosis (SSc) since the earliest phases. Our aim is to perform an ultrastructural study on skin PNS fibers in SSc. Methods.
D. Melchiorre, S. Guiducci, S. Generini, A. Franca Milia, D. Nosi, A. Tani, L. Ibba Manneschi, A. Del Rosso, A. Pignone, M. Matucci Cerinic   +9 more
doaj   +1 more source

Peripheral nervous system involvement in systemic amyloidosis

Неврология, нейропсихиатрия, психосоматика, 2018
Peripheral nervous system involvement may be a main manifestation of systemic amyloidosis or occur in the later stages of the disease in the presence of multiple organ pathology.
E. I. Safiulina, O. E. Zinovyeva, V. V. Rameev, L. V. Kozlovskaya-Lysenko   +3 more
doaj   +1 more source

Living with Duchenne Muscular Dystrophy Beyond the Physical Implications: Cognitive Features, Psychopathology Aspects, and Psychosocial Resources—A Narrative Review

Brain Sciences
Background/Objectives: Duchenne muscular dystrophy (DMD) is often discussed in the literature with regard to physical impairments. This narrative review aims to show that living with DMD involves psychological, psychosocial, and cognitive aspects in ...
Federica Tizzoni, Giulia Canella, Antonella Delle Fave, Daniele Di Lernia, Maria Luisa Lorusso, Maria Nobile, Maria Grazia D’Angelo   +6 more
doaj   +1 more source

Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms

Scientific Reports, 2017
Impairment of peripheral neurons by anti-cancer agents, including taxanes and platinum derivatives, has been considered to be a major cause of chemotherapy-induced peripheral neuropathy (CIPN), however, the precise underlying mechanisms are not fully ...
Satoshi Imai, Madoka Koyanagi, Ziauddin Azimi, Yui Nakazato, Mayuna Matsumoto, Takashi Ogihara, Atsushi Yonezawa, Tomohiro Omura, Shunsaku Nakagawa, Shuji Wakatsuki, Toshiyuki Araki, Shuji Kaneko, Takayuki Nakagawa, Kazuo Matsubara   +13 more
doaj   +1 more source

Quantitative thermal sensory testing and sympathetic skin response in primary Restless legs syndrome - A prospective study on 57 Indian patients

Annals of Indian Academy of Neurology, 2012
Patients with restless leg syndrome present with sensory symptoms similar to peripheral neuropathy. While there is evidence of abnormalities of dopaminergic pathways, the peripheral nervous system has been studied infrequently.
Garima Shukla, Vinay Goyal, Achal Srivastava, Madhuri Behari   +3 more
doaj   +1 more source

Muscarinic receptor oligomerization [PDF]

, 2018
G protein-coupled receptors (GPCRs) have been classically described as monomeric entities that function by binding in a 1:1 stoichiometric ratio to both ligand and downstream signalling proteins.
Alvarez-Curto, Elisa, Marsango, Sara, Milligan, Graeme, Ward, Richard J.   +3 more
core   +1 more source

Toward European harmonization of national myasthenia gravis registries: modified Delphi procedure-based expert consensus on collectable data

Orphanet Journal of Rare Diseases
Background Myasthenia gravis (MG) is a rare autoimmune disorder. Several new treatment concepts have emerged in recent years, but access to these treatments varies due to differing national reimbursement regulations, leading to disparities across Europe.
Abderhmane Slioui, Giulia Tammam, Fiammetta Vanoli, Adela Della Marina, Stanislav Vohanka, Nils Erik Gilhus, Isabella Moroni, Maria Isabel Leite, Fredrik Piehl, Carlo Antozzi, Jonathan Pini, Frauke Stascheit, Shahram Attarian, Ernestina Santos, Jan Verschuuren, Lou Canonge, Jeremy Garcia, Caroline Perriard, Elena Cortés-Vicente, Renato Mantegazza, Andreas Meisel, Sabrina Sacconi   +21 more
doaj   +1 more source

Alpha- synuclein immunoreactivity in the enteric nervous system of human small intestine [PDF]

, 2018
Alpha-synuclein (α-syn) is a 140 amino acid protein, belonging to the synuclein family, expressed in mammalian neurons. Structural alterations of α-syn as well as its overexpression have been related to the onset and the progression of several human ...
Casini, Arianna, Chirletti, Piero, Vaccaro, Rosa   +2 more
core  

Rapid testing leads to the underestimation of the scrapie prevalence in an affected sheep and goat flock [PDF]

, 2007
To obtain a more detailed understanding of the prevalence of classical scrapie infections in a heavily affected German sheep flock (composed of 603 sheep and 6 goats), we analysed 169 sheep and 6 goats that carried the genotypes susceptible to the ...
Bellmann, Steffi, Buda, Silke, Budras, Klaus-Dieter, Buschmann, Anne, Erhardt, Georg, Fries, Reinhard, Groschup, Martin H., Hoffmann, Christine, Knobloch, Hartmut, Reckling, Karl-Friedrich, Reckzeh, Claudia   +10 more
core   +2 more sources