Results 51 to 60 of about 1,729,325 (383)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Long term clinical outcomes of minimally invasive transforaminal interbody fusion (MIS-TLIF) for lumbar spondylolisthesis in a geriatric (>65 years) population: a systematic review and meta-analysis

open access: yesFrontiers in Surgery
IntroductionThe minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) technique has become a popular and effective option for treating lumbar degenerative spondylolisthesis, especially in elderly patients.
Talgat Kerimbayev   +3 more
doaj   +1 more source

PERIPHERAL NERVOUS SYSTEM INVOLVEMENT IN LYMPHOPROLIFERATIVE DISORDERS

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2018
Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable ...
Mario Sabatelli   +2 more
doaj   +1 more source

Musculoskeletal and Peripheral Nervous System Involvement in a Patient Undergoing Chronic Hemodialysis: A Case Report and Literature Review

open access: yesTürk Osteoporoz Dergisi, 2021
Musculoskeletal system manifestations in chronic renal insufficiency are caused by complex bone metabolism alterations, which is now described under the umbrella term of chronic kidney disease mineral- and bone-related disorder instead of renal ...
Zeynep Tuba Bahtiyarca   +1 more
doaj   +1 more source

Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]

open access: yesarXiv, 2022
Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv  

Expression patterns of Slit and Robo family members in adult mouse spinal cord and peripheral nervous system

open access: yesPLoS ONE, 2017
The secreted glycoproteins, Slit1-3, are classic axon guidance molecules that act as repulsive cues through their well characterised receptors Robo1-2 to allow precise axon pathfinding and neuronal migration.
Lauren Carr, D. Parkinson, X. Dun
semanticscholar   +1 more source

Microglia Involvement into Acute and Chronic Brain Damage in Diabetic Rats: Impact of GLP-1RA and SGLT-2i

open access: yesFrontiers in Bioscience-Landmark
Background: Acute and chronic brain damage in type 2 diabetes mellitus (DM) determines the need to investigate the neuroprotective potential of glucose-lowering drugs.
Anna Simanenkova   +8 more
doaj   +1 more source

Peripheral nervous system in limited systemic sclerosis

open access: yesReumatismo, 2011
Objectives. PNS is involved in Systemic Sclerosis (SSc) since the earliest phases. Our aim is to perform an ultrastructural study on skin PNS fibers in SSc. Methods.
D. Melchiorre   +9 more
doaj   +1 more source

Relationship between acupuncture and transient receptor potential vanilloid: Current and future directions

open access: yesFrontiers in Molecular Neuroscience, 2022
Acupuncture is a common complementary and alternative therapy around the world, but its mechanism remains still unclear. In the past decade, some studies indicated that transient receptor potential vanilloid (TRPV) channels play a great role in the ...
Dan Luo   +10 more
doaj   +1 more source

Optical coherence tomography imaging of evoked neural activity in sciatic nerve of rat [PDF]

open access: yes, 2020
Significance: Imaging neural activity in myelinated tissue using optical coherence tomography (OCT) creates new possibilities for functional imaging in the peripheral and central nervous systems. Aim: To investigate changes in OCT images in response to evoked neural activity in sciatic nerve of rat in vitro.
arxiv   +1 more source

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