Results 1 to 10 of about 448,698 (356)

Cholinergic Modulation of the Immune System in Neuroinflammatory Diseases

open access: yesDiseases, 2021
Frequent diseases of the CNS, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and psychiatric disorders (e.g., schizophrenia), elicit a neuroinflammatory response that contributes to the neurodegenerative disease process itself. The
Marcella Reale, Erica Costantini
doaj   +1 more source

Autoimmune Disorders of the Nervous System: Pathophysiology, Clinical Features, and Therapy

open access: yesFrontiers in Neurology, 2021
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of several, previously poorly understood, neurological disorders.
Satyakam Bhagavati
doaj   +1 more source

Conduction Block in the Peripheral Nervous System in Experimental Allergic Encephalomyelitis [PDF]

open access: yes, 1982
Experimental Allergic Encephalomyelitis (EAE) has been widely studied as a model of multiple sclerosis, a central nervous system (CNS) disease of unknown aetiology.
Pender, M. P., Sears, T. A.
core   +1 more source

Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs [PDF]

open access: yes, 2020
In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by
Chen, Xiaohong   +15 more
core   +1 more source

Clinical diagnosis and treatment recommendations for immune checkpoint inhibitor‐related adverse reactions in the nervous system

open access: yesThoracic Cancer, 2020
Immune checkpoint inhibitors (ICIs) can cause adverse reactions in the nervous system. The incidence rate is 0.1%–12% and 80% of nervous system adverse reactions occur within the first four months of application.
Jiayu Shi   +9 more
doaj   +1 more source

Neurological Diseases: Cause and Effect in the Era of COVID-19

open access: yesSVU - International Journal of Medical Sciences, 2021
Background: SARS-CoV-2 new infectious disease was first reported in Wuhan, China in December 2019. Thereafter, it has extensively spread causing global pandemic. It was named as corona virus disease 2019 (COVID-19) by WHO in February 2020. Other than the
Islam Elmalky *   +2 more
doaj   +1 more source

Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]

open access: yes, 2019
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
core   +1 more source

Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]

open access: yes, 2018
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu   +82 more
core   +2 more sources

Value of Neurofilament Light Chain as a Biomarker in Peripheral Neuropathy [PDF]

open access: yesZhongguo quanke yixue, 2022
Neurofilament light chain (NfL) has been identified as a biomarker of axonal injury in a variety of central nervous system diseases. The value of NfL as a biomarker in peripheral neuropathy has gained increasing attention.
SUN Xiaoling, HUANG Kaiwei, WAN Xinbei, WU Ying, LI Zhijun
doaj   +1 more source

Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]

open access: yes, 2017
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M   +183 more
core   +1 more source

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