Results 1 to 10 of about 1,364,257 (408)

The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]

open access: yes, 2017
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela   +3 more
core   +8 more sources

The therapeutic potential of natural killer cells in neuropathic pain [PDF]

open access: yes, 2023
Novel, disease-modifying treatments for neuropathic pain are urgently required. The cellular immune response to nerve injury represents a promising target for therapeutic development.
Davies, Alexander   +3 more
core   +2 more sources

Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]

open access: yes, 2019
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
core   +1 more source

CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems [PDF]

open access: yes, 2019
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Amani Wehbi   +7 more
core   +2 more sources

Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]

open access: yes, 2018
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu   +82 more
core   +2 more sources

Conduction Block in the Peripheral Nervous System in Experimental Allergic Encephalomyelitis [PDF]

open access: yes, 1982
Experimental Allergic Encephalomyelitis (EAE) has been widely studied as a model of multiple sclerosis, a central nervous system (CNS) disease of unknown aetiology.
Pender, M. P., Sears, T. A.
core   +1 more source

Clinical and Pharmacological Aspects of Inflammatory Demyelinating Diseases in Childhood: An Update [PDF]

open access: yes, 2010
Inflammatory demyelinating diseases comprise a spectrum of disorders affecting the myelin of the central and peripheral nervous system. These diseases can usually be differentiated on the basis of clinical, radiological, laboratory and pathological ...
Del Balzo, Francesca   +9 more
core   +2 more sources

The Pathophysiology of Acute Experimental Allergic Encephalomyelitis in the Rabbit [PDF]

open access: yes, 1983
Clinical, histological and electrophysiological studies were performed on rabbits with acute experimental allergic encephalomyelitis (EAE). The clinical features were similar to those previously described, with the notable exception of the new findings ...
Pender, M. P., Sears, T. A.
core   +3 more sources

Peripheral Neuropathy [PDF]

open access: yes, 2021
Over the last two decades we have seen extensive progress within the practice of neurology. We have refined our understanding of the etiology and pathogenesis for both peripheral and central nervous system diseases, and developed new therapeutic ...

core   +1 more source

Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain [PDF]

open access: yes, 2012
Prion diseases are subacute neurodegenerative diseases that affect humans and a range of domestic and free-ranging animal species. These diseases are characterized by the accumulation of PrP(Sc), an abnormally folded isoform of the cellular prion protein
Mabbott, N. A.
core   +1 more source

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