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The Peripheral Nervous System and the Pathogenesis of Prion Diseases [PDF]

open access: greenCurrent Molecular Medicine, 2004
Prion diseases are inevitably fatal neurodegenerative conditions which affect humans and a wide variety of animals. Unlike other protein aggregation diseases such as Alzheimer's, Parkinson's, and polyglutamine repeat diseases, prion diseases are unique in that they are transmissible.
Markus Glatzel   +3 more
openalex   +5 more sources

Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System [PDF]

open access: yesFrontiers in Neuroscience, 2019
In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye   +11 more
doaj   +3 more sources

Peripherin is a biomarker of axonal damage in peripheral nervous system disease

open access: hybridBrain, 2023
Abstract Valid, responsive blood biomarkers specific to peripheral nerve damage would improve management of peripheral nervous system (PNS) diseases. Neurofilament light chain (NfL) is sensitive for detecting axonal pathology but is not specific to PNS damage, as it is expressed throughout the PNS and CNS.
Stephen Keddie   +15 more
openalex   +5 more sources

PERIPHERAL NERVOUS SYSTEM INVOLVEMENT IN LYMPHOPROLIFERATIVE DISORDERS [PDF]

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2018
Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable ...
Mario Sabatelli   +2 more
doaj   +3 more sources

Impact of intestinal disorders on central and peripheral nervous system diseases

open access: yesNeurobiology of Disease, 2022
Brain injuries and neurological diseases have a significant impact on the gut microbiome and the gut barrier. Reciprocally, gut disorders, such as Inflammatory Bowel Syndromes (IBS), can affect the development and pathology of neurodegenerative and ...
Yumna El-Hakim   +3 more
doaj   +3 more sources

The Role and Mechanism of Metformin in the Treatment of Nervous System Diseases. [PDF]

open access: yesBiomolecules
Nervous system diseases represent a significant global burden, affecting approximately 16% of the world’s population and leading to disability and mortality.
Li H, Liu R, Liu J, Qu Y.
europepmc   +2 more sources

Peripheral nervous system involvement in patients with sickle cell disease [PDF]

open access: bronzeEuropean Journal of Neurology, 2009
Peripheral nervous system involvement is rare in sickle cell disease (SCD). The aim of this study is to determine the peripheral nerve involvement electrophysiologically in SCD patients without clinically evident neurological signs, symptoms and to determine the relationship between the frequency of sickle cell crisis and peripheral neuropathy.Fifty ...
Esra Okuyucu   +5 more
openalex   +3 more sources

The therapeutic potential of natural killer cells in neuropathic pain [PDF]

open access: yes, 2023
Novel, disease-modifying treatments for neuropathic pain are urgently required. The cellular immune response to nerve injury represents a promising target for therapeutic development.
Davies, Alexander   +3 more
core   +2 more sources

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