Results 1 to 10 of about 448,698 (356)
Cholinergic Modulation of the Immune System in Neuroinflammatory Diseases
Frequent diseases of the CNS, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and psychiatric disorders (e.g., schizophrenia), elicit a neuroinflammatory response that contributes to the neurodegenerative disease process itself. The
Marcella Reale, Erica Costantini
doaj +1 more source
Autoimmune Disorders of the Nervous System: Pathophysiology, Clinical Features, and Therapy
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of several, previously poorly understood, neurological disorders.
Satyakam Bhagavati
doaj +1 more source
Conduction Block in the Peripheral Nervous System in Experimental Allergic Encephalomyelitis [PDF]
Experimental Allergic Encephalomyelitis (EAE) has been widely studied as a model of multiple sclerosis, a central nervous system (CNS) disease of unknown aetiology.
Pender, M. P., Sears, T. A.
core +1 more source
Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs [PDF]
In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by
Chen, Xiaohong+15 more
core +1 more source
Immune checkpoint inhibitors (ICIs) can cause adverse reactions in the nervous system. The incidence rate is 0.1%–12% and 80% of nervous system adverse reactions occur within the first four months of application.
Jiayu Shi+9 more
doaj +1 more source
Neurological Diseases: Cause and Effect in the Era of COVID-19
Background: SARS-CoV-2 new infectious disease was first reported in Wuhan, China in December 2019. Thereafter, it has extensively spread causing global pandemic. It was named as corona virus disease 2019 (COVID-19) by WHO in February 2020. Other than the
Islam Elmalky *+2 more
doaj +1 more source
Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
core +1 more source
Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu+82 more
core +2 more sources
Value of Neurofilament Light Chain as a Biomarker in Peripheral Neuropathy [PDF]
Neurofilament light chain (NfL) has been identified as a biomarker of axonal injury in a variety of central nervous system diseases. The value of NfL as a biomarker in peripheral neuropathy has gained increasing attention.
SUN Xiaoling, HUANG Kaiwei, WAN Xinbei, WU Ying, LI Zhijun
doaj +1 more source
Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M+183 more
core +1 more source