The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela+3 more
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The therapeutic potential of natural killer cells in neuropathic pain [PDF]
Novel, disease-modifying treatments for neuropathic pain are urgently required. The cellular immune response to nerve injury represents a promising target for therapeutic development.
Davies, Alexander+3 more
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Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Amato, Antonella, Mulè, Flavia
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CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems [PDF]
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Amani Wehbi+7 more
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Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu+82 more
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Conduction Block in the Peripheral Nervous System in Experimental Allergic Encephalomyelitis [PDF]
Experimental Allergic Encephalomyelitis (EAE) has been widely studied as a model of multiple sclerosis, a central nervous system (CNS) disease of unknown aetiology.
Pender, M. P., Sears, T. A.
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Clinical and Pharmacological Aspects of Inflammatory Demyelinating Diseases in Childhood: An Update [PDF]
Inflammatory demyelinating diseases comprise a spectrum of disorders affecting the myelin of the central and peripheral nervous system. These diseases can usually be differentiated on the basis of clinical, radiological, laboratory and pathological ...
Del Balzo, Francesca+9 more
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The Pathophysiology of Acute Experimental Allergic Encephalomyelitis in the Rabbit [PDF]
Clinical, histological and electrophysiological studies were performed on rabbits with acute experimental allergic encephalomyelitis (EAE). The clinical features were similar to those previously described, with the notable exception of the new findings ...
Pender, M. P., Sears, T. A.
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Over the last two decades we have seen extensive progress within the practice of neurology. We have refined our understanding of the etiology and pathogenesis for both peripheral and central nervous system diseases, and developed new therapeutic ...
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Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain [PDF]
Prion diseases are subacute neurodegenerative diseases that affect humans and a range of domestic and free-ranging animal species. These diseases are characterized by the accumulation of PrP(Sc), an abnormally folded isoform of the cellular prion protein
Mabbott, N. A.
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