Results 91 to 100 of about 1,092,875 (381)

Matrix metalloproteinases as new targets in Alzheimer's disease: Opportunities and Challenges [PDF]

open access: yesJournal of Medicinal Chemistry, American Chemical Society, 2020, 2021
Although matrix metalloproteinases (MMPs) are implicated in the regulation of numerous physiological processes, evidences of their pathological roles have also been obtained in the last decades, making MMPs attractive therapeutic targets for several diseases.
arxiv  

The Longitudinal Relationship Between Pain and Depression in People with Inflammatory Arthritis: a Narrative Review

open access: yesArthritis Care &Research, Accepted Article.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Co‐morbid depression is prevalent in adults with IA, affecting 15 to 39% of people. Whilst pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox   +3 more
wiley   +1 more source

Clinical analysis on two patients with N-hexane toxic peripheral neuropathy misdiagnosed as chronic inflammatory demyelinating polyradiculoneuropathy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the clinical and neuropathological features of N-hexane toxic peripheral neuropathy which was misdiagnosed as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Yi LI   +7 more
doaj  

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

Glymphatic system: a gateway for neuroinflammation

open access: yesNeural Regeneration Research
The glymphatic system is a relatively recently identified fluid exchange and transport system in the brain. Accumulating evidence indicates that glymphatic function is impaired not only in central nervous system disorders but also in systemic diseases ...
Kailu Zou   +3 more
doaj   +1 more source

Peripheral neuropathy in inflammatory joint diseases [PDF]

open access: yes, 2018
Background: For frequent extra-articular (systemic) manifestations of joints inflammatory diseases are various damage of the nervous system,2 and the presence and severity of peripheral neuropathy (PNP) have significance in the clinical course, which ...
Bevzenko, T.   +2 more
core  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

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