Results 91 to 100 of about 657,989 (383)

The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases

open access: yesJournal of Aging Research, 2016
The ongoing epidemics of metabolic diseases and increase in the older population have increased the incidences of neurodegenerative diseases. Evidence from murine and cell line models has implicated calcineurin-nuclear factor of activated T-lymphocytes ...
M. Kipanyula, W. Kimaro, P. F. Seke Etet
semanticscholar   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

open access: yes, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce   +7 more
core   +1 more source

T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis [PDF]

open access: yes, 2020
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the progressive loss of axonal myelin in several areas of the central nervous system (CNS) that is responsible for clinical symptoms such as muscle spasms, optic neuritis ...
Amormino, Carola   +4 more
core   +1 more source

Central and peripheral nervous system involvement caused by Zika and chikungunya coinfection

open access: yesPLoS Neglected Tropical Diseases, 2017
1 Department of Clinical Medicine, Federal University of Pernambuco UFPE, Recife, Brazil, 2 Department of Neurology, Santa Joana Hospital, Recife, Brazil, 3 Department of Virology and Experimental Therapy, Oswaldo Cruz Foundation FIOCRUZ, Aggeu Magalhães
C. Brito   +4 more
semanticscholar   +1 more source

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu   +7 more
wiley   +1 more source

The Lin28/let-7 axis is critical for myelination in the peripheral nervous system

open access: yesNature Communications, 2015
MicroRNAs (miRNAs) are crucial regulators of myelination in the peripheral nervous system (PNS). However, the miRNAs species involved and the underlying mechanisms are largely unknown. We found that let-7 miRNAs are highly abundant during PNS myelination
Deniz Gökbuget   +7 more
semanticscholar   +1 more source

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