The Peripheral Nervous System and the Pathogenesis of Prion Diseases [PDF]
Prion diseases are inevitably fatal neurodegenerative conditions which affect humans and a wide variety of animals. Unlike other protein aggregation diseases such as Alzheimer's, Parkinson's, and polyglutamine repeat diseases, prion diseases are unique in that they are transmissible.
Glatzel, M+3 more
semanticscholar +6 more sources
Peripherin is a biomarker of axonal damage in peripheral nervous system disease
Abstract Valid, responsive blood biomarkers specific to peripheral nerve damage would improve management of peripheral nervous system (PNS) diseases. Neurofilament light chain (NfL) is sensitive for detecting axonal pathology but is not specific to PNS damage, as it is expressed throughout the PNS and CNS.
Keddie, S+15 more
semanticscholar +6 more sources
A review on recent advances on nobiletin in central and peripheral nervous system diseases. [PDF]
In recent years, the role of nobiletin in neuronal disorders has received extensive attention. However, the study of nobiletin in the peripheral nervous system is limited.
Pang Y, Xiong J, Wu Y, Ding W.
europepmc +2 more sources
Peripheral Nervous System Manifestations of Infectious Diseases [PDF]
Infectious causes of peripheral nervous system (PNS) disease are underrecognized but potentially treatable. Heightened awareness educed by advanced understanding of the presentations and management of these infections can aid diagnosis and facilitate treatment.
Jennifer L. Lyons, Kate Brizzi
openaire +4 more sources
A 3D disease and regeneration model of peripheral nervous system–on–a–chip [PDF]
A 3D PNS disease–on–a–chip enables the monitoring of pathophysiological processes, including demyelination and remyelination.
Sujin Hyung+6 more
openaire +3 more sources
Peripheral nervous system diseases and pregnancy
113 pregnant women with periferal nervous system diseases(PNSD) are examined. 84 of them had radiculoneuropathy: 48 - lumbosacral segment (LSS), 36 - cervicothoracal segment (CTS), 29 had single and multiple neuropathy (SMN). Almost half cases (49,6%) the symptoms of PNSD first appeared in 2nd trimester.
V. D. Ryzkov+2 more
openaire +4 more sources
Focus on 1,25-Dihydroxyvitamin D3 in the Peripheral Nervous System
In this review, we draw attention to the roles of calcitriol (1,25-dihydroxyvitamin D3) in the trophicity of the peripheral nervous system. Calcitriol has long been known to be crucial in phosphocalcium homeostasis. However, recent discoveries concerning
Pierre Antoine Faye+11 more
doaj +2 more sources
Autoimmune Disorders of the Nervous System: Pathophysiology, Clinical Features, and Therapy
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of several, previously poorly understood, neurological disorders.
Satyakam Bhagavati
doaj +2 more sources
Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease [PDF]
Neurosteroids are steroid hormones synthesised de novo in the brain and peripheral nervous tissues. In contrast to adrenal steroid hormones that act on intracellular nuclear receptors, neurosteroids directly modulate plasma membrane ion channels and ...
Emyr Lloyd–Evans, Helen Waller‐Evans
openalex +2 more sources
Impact of intestinal disorders on central and peripheral nervous system diseases
Brain injuries and neurological diseases have a significant impact on the gut microbiome and the gut barrier. Reciprocally, gut disorders, such as Inflammatory Bowel Syndromes (IBS), can affect the development and pathology of neurodegenerative and neuropsychiatric diseases, although this aspect is less well studied and is the focus of this review ...
Yumna El-Hakim+3 more
openaire +4 more sources