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Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy
Neural Regeneration Research, 2022 Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting nerves in all parts of the body including corneal nerves and peripheral nervous system, leading to diabetic corneal neuropathy and diabetic peripheral ...
Wei Zheng So +6 more
doaj +2 more sources
Diagnosis of peripheral neuropathy [PDF]
Neurological Research and Practice, 2020 Abstract Introduction Peripheral neuropathy represents a spectrum of diseases with different etiologies. The most common causes are diabetes, exposure to toxic substances including alcohol and chemotherapeutics, immune-mediated conditions, and gene mutations.
Lehmann, Helmar C. +3 more
openaire +6 more sources
Medical Clinics of North America, 2019 Peripheral neuropathy is a commonly encountered disorder in clinical practice. In light of an aging population and the diabetes and obesity pandemic, the prevalence of peripheral neuropathy is increasing, posing a significant public health concern. This article provides a diagnostic framework for neuropathies and summarizes treatment options.
Kelsey, Barrell, A Gordon, Smith
openaire +3 more sources
Scientific Reports, 2021 Peripheral neuropathy is associated with substantial morbidity, but risk factors other than diabetes are largely uncharacterized. The aim of this study was to describe the prevalence and risk factors for peripheral neuropathy in adults with and without ...
Caitlin W. Hicks +4 more
doaj +2 more sources
Peripheral neuropathy in metachromatic leukodystrophy: current status and future perspective
Orphanet Journal of Rare Diseases, 2019 Metachromatic leukodystrophy (MLD) is an autosomal recessively inherited metabolic disease characterized by deficient activity of the lysosomal enzyme arylsulfatase A.
Shanice Beerepoot +5 more
doaj +2 more sources
Biomedicines, 2022 Paclitaxel is a widely used anticancer drug that induces dose-limiting peripheral neuropathy. Mitochondrial dysfunction has been implicated in paclitaxel-induced neuronal damage and in the onset of peripheral neuropathy. We have previously shown that the
Hye-Ji Jang +4 more
doaj +1 more source
Insulin-regulated serine and lipid metabolism drive peripheral neuropathy
Nature, 2023 Serine deficiency can increase small fibre neuropathy in wild-type mice and serine replacement in diabetic mice alleviates diabetic neuropathy, directly linking amino acid metabolism to peripheral nerve disorders.
Michal K. Handzlik +21 more
semanticscholar +1 more source
Pharmaceuticals, 2021 Preclinical evidence, accumulated over the past decade, indicates that the angiotensin II type 2 receptor (AT2R) stimulation exerts significant neuroprotective effects in various animal models of neuronal injury, notably in the central nervous system ...
Aurore Danigo +9 more
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Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID
Neurology: Neuroimmunology & Neuroinflammation, 2022 Background and Objectives Recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection appears exponential, leaving a tail of patients reporting various long COVID symptoms including unexplained fatigue/exertional intolerance and ...
A. Oaklander +6 more
semanticscholar +1 more source
Ramipril Alleviates Oxaliplatin-Induced Acute Pain Syndrome in Mice
Frontiers in Pharmacology, 2021 Oxaliplatin is a key drug for colorectal cancer that causes OXP-induced peripheral neuropathy, a dose-limiting effect characterized by cold and tactile hyperesthesia.
Hichem Bouchenaki +10 more
doaj +1 more source