Results 141 to 150 of about 371,827 (350)

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Romidepsin in peripheral and cutaneous T‐cell lymphoma: mechanistic implications from clinical and correlative data

, 2015
Susan E. Bates, Robin A. Eisch, Alexander Ling, Douglas R. Rosing, Maria L. Turner, Stefania Pittaluga, H. Miles Prince, Mark Kirschbaum, Steven L. Allen, Jasmine Zain, Larisa J. Geskin, David Joske, Leslie Popplewell, Edward W. Cowen, Elaine S. Jaffe, Jean Nichols, Sally Kennedy, Seth M. Steinberg, David J. Liewehr, Louise C. Showe, Caryn Steakley, James R. Wright, Tito Fojo, Thomas Litman, Richard Piekarz   +24 more
openalex   +2 more sources

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Analysis of clinical characteristics and prognosis of patients with peripheral T-cell lymphoma

, 2021
Xiao Liang, Li Guo, Xin Hu, Shan Li, Shujuan Wen   +4 more
openalex   +1 more source

Molecular insights into pathogenesis and targeted therapy of peripheral T cell lymphoma [PDF]

, 2020
Caiqin Xie, Xian Li, Hui Zeng, Wenbin Qian   +3 more
openalex   +1 more source

Effect of medicinal and food homologous plants polysaccharides on animal nutrition and health: A review

Food Biomacromolecules, EarlyView.
Abstract As one of the most important components of foods, animal meat provides a lot of protein, fat, and energy for humans. However, nutrition and health of animals directly affect the healthiness of human, especially antibiotic residues in animals induced by abuse of antibiotics.
Zichao Wang, Yi Zheng, Changxing Liu, Danye Zhu, Yingjie Feng, Hongtao Zhang, Qi Wang, Qinggong Chen, Xueyi Qiao   +8 more
wiley   +1 more source

ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project.

Blood, 2008
K. Savage, N. Harris, J. Vose, F. Ullrich, E. Jaffe, J. Connors, L. Rimsza, S. Pileri, M. Chhanabhai, R. Gascoyne, J. Armitage, D. Weisenburger   +11 more
semanticscholar   +1 more source

Guideline for the In Vivo Immunomodulatory Activity Test of Polysaccharide Based on Cyclophosphamide‐Induced Mouse Model

Food Safety and Health, EarlyView.
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie, Xuecong Tong, Qiao Ding, Xiaojun Huang   +3 more
wiley   +1 more source

The prognostic significance of lymphopenia in peripheral T‐cell and natural killer/T‐cell lymphomas: A study of 826 cases from the International Peripheral T‐cell Lymphoma Project

, 2012
Zdravko Mitrović, Anamarija M. Perry, Junji Suzumiya, J. O. Armitage, Wing Y. Au, Bertrand Coiffier, Harald Holte, Elaine S. Jaffe, Emili Monserrat, Sandeep K. Rajan, Kerry J. Savage, Kensei Tobinai, Julie M. Vose, Dennis D. Weisenburger   +13 more
openalex   +2 more sources

Peripheral T-Cell Lymphoma Mimicking Marginal Zone B-Cell Lymphoma [PDF]

, 2002
Patricia Uherova, Charles W. Ross, William G. Finn, Timothy P. Singleton, Rina Kansal, Bertram Schnitzer   +5 more
openalex   +1 more source