Results 131 to 140 of about 1,895,537 (160)

Combined Pharmacologic and Nutritional Modulation of High-Fat Diet-Associated Tumor-Supportive Features in Prostate Cancer Models. [PDF]

Biomolecules
Wu K, Hao Q, Yang J, Elshimali Y, Magyar CE, Henning SM, Andalibi A, Wang P.   +7 more
europepmc   +1 more source

Editor Note to article entitled “A modified U-Net convolutional neural network for segmenting periprostatic adipose tissue based on contour feature learning”

Heliyon
doaj   +1 more source

Periprostatic Adipose Tissue Thromboinflammation Triggers Prostatic Neoplasia in Early Metabolic Impairment: Interruption by Rivaroxaban [PDF]

Life Sciences, 2023
Prostate cancer is among the highest incidence malignancies in men with a prevalence rate increasing in parallel to the rising global trends in metabolic disorders. Whereas a sizeable body of evidence links metabolic impairment to negative prognosis of prostate cancer, the molecular mechanism underlying this connection has not been thoroughly examined.
Ibrahim Alzaim, Wassim Abou-Kheir, Nadine Darwiche   +2 more
exaly   +4 more sources

Anatomic Distribution of Periprostatic Adipose Tissue [PDF]

Cancer, 2003
AbstractBACKGROUNDBecause the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively.METHODSThe authors analyzed the ...
Liang Cheng, Thomas Gardner, Thomas M. Ulbright   +2 more
exaly   +3 more sources

Changes in Periprostatic Adipose Tissue Induced by 5α-Reductase Inhibitors [PDF]

Andrology, 2017
SummaryThere is increasing interest in periprostatic fat and its influence on prostate cancer aggressiveness. In vitro data suggest that adipose stromal/stem cells (ASCs) can increase production of cytokines and growth factors resulting in invasive growth and metastasis in prostate cancer.
M Barkati, G Delouya
exaly   +3 more sources

Human Periprostatic Adipose Tissue: Its Influence on Prostate Cancer Cells [PDF]

Cellular Physiology and Biochemistry, 2012
Adipose microenvironment is involved in signaling pathways that influence prostate cancer (PCa) progression. However, the role of human periprostatic adipose tissue (PPAT) from patients with benign prostatic hyperplasia (BPH) has not been studied and compared to that of PPAT from PCa patients.
Sabrina Johanna Fletcher, Hosoon Choi
exaly   +4 more sources

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Lipophagy and Prostate Cancer: Association With Disease Aggressiveness and Proximity to Periprostatic Adipose Tissue

Journal of Pathology, 2021
AbstractThe prostate gland is surrounded by periprostatic adipose tissue (PPAT), which is believed to play a role in prostate cancer (PCa) progression. Cancer cells can take up lipids from the microenvironment and store them in lipid droplets (LDs). Fatty acids released from LDs are used by PCa cells as preferential metabolic fuels to provide energy ...
Lucie Brisson, Gaelle Fromont, Franck Bruyere   +2 more
exaly   +3 more sources

Periprostatic Adipose Tissue as a Modulator of Prostate Cancer Aggressiveness

Journal of Urology, 2009
Adipose tissue has been suggested to contribute to the pathogenesis of various disease states, including prostate cancer. We investigated the association of cytokines and growth factors secreted by periprostatic adipose tissue with pathological features of aggressive prostate cancer.Periprostatic adipose tissue was harvested from patients undergoing ...
David S, Finley, Valerie S, Calvert, Junichi, Inokuchi, Alice, Lau, Navneet, Narula, Emanuel F, Petricoin, Frank, Zaldivar, Rosanne, Santos, Darren R, Tyson, David K, Ornstein   +9 more
openaire   +3 more sources