Results 251 to 260 of about 830,673 (331)

Great Debate: Hyperthermic Intraperitoneal Chemotherapy for Colorectal Peritoneal Metastases-Should It Be Offered? [PDF]

Ann Surg Oncol
Foster JM, Nash GM, Möller MG.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, Volume 20, Issue 9, Page 2188-2202, September 2026.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

PICCOS: study protocol for pressurised intraperitoneal aerosolised chemotherapy (PIPAC) in the management of cancers of the colon, ovary and stomach: a randomised controlled, phase II trial of efficacy in peritoneal metastases. [PDF]

Pleura Peritoneum
Jones SEF, Brogden E, Murphy J, Peters CJ, Frost J, Adams R, Gwynne S, Hudson E, Perry K, Casbard A, Hamilton R, Nixon L, Markham P, Mohamed H, Brown G, Blazeby J, Fitzsimmons D, Ajakaiye A, Batten LM, Edgar M, Case A, Kyle P, Tate S, Arndell K, Elliott D, Macefield R, Chuter D, Hall H, Garfitt J, Torkington J.   +29 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Clinical efficacy of Xiaotan Sanjie decoction in treating gastric cancer with peritoneal metastases: A study protocol for a randomized controlled trial. [PDF]

Contemp Clin Trials Commun
Li QY, Li X, Liu H, Lu Y, Guo ZW, Qiu WC, Wei PK, Shi J.   +7 more
europepmc   +1 more source

Artificial intelligence‐assisted histopathological diagnosis of endocervical gastric‐type adenocarcinoma: a multicenter model development and validation study

The Journal of Pathology: Clinical Research, Volume 12, Issue 5, September 2026.
Abstract Endocervical gastric‐type adenocarcinoma (GAS) is one of the most aggressive subtypes of cervical cancer and is frequently underdiagnosed due to morphological ambiguity, leading to delayed diagnosis. Despite the availability of molecular and genomic assays, their high cost, complexity, and limited reproducibility restrict clinical use.
Jing Yang, Qiming He, Jing Peng, Yizhi Wang, Jiawen Li, Haoxiang Li, Yan Liu, Yuxiang Wang, Ajin Hu, Xitong Ling, Yingwen Zhang, Minxi Ouyang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Yexing Zhang, Siqi Zeng, Qiang Huang, Zihan Wang, Tian Guan, Yueping Liu, Ling Chen, Yan Ding, Yonghong He, Congrong Liu   +24 more
wiley   +1 more source

An Unexpected Twist: Sigmoid Volvulus Complicated by Peritoneal Metastases. [PDF]

Cureus
Mohiuddin A, Hussain F, Denha E, Schad C, Antaki F, Rifkin S.   +5 more
europepmc   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Immunotherapy Plus Surgery Improves Survival in Microsatellite Instability-High Colon Cancer with Isolated Peritoneal Metastases. [PDF]

Cancers (Basel)
Metzger DA, Chahal Y, Watman O, Li Y, Pigazzi A, Siolas D, Jafari MD.   +6 more
europepmc   +1 more source

Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang, Jintian Yu, Liang Yuan, Ziliang Fu, Yiming Yao, Lingna Chen, Shixiong Chen, Aikemu Ainiwaer, Xiaolin Cui   +8 more
wiley   +1 more source