Results 231 to 240 of about 830,673 (331)

Plasma PlGF as a Potential Biomarker in Ramucirumab‐Based Second‐Line Therapy for Advanced Gastroesophageal Adenocarcinoma: Exploratory Biomarker Analysis from the Phase II Part of the RAMIRIS Trial

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1817-1828, 1 October 2026.
Antiangiogenic treatment with ramucirumab is a standard second‐line option in advanced gastric and gastroesophageal junction adenocarcinoma. However, reliable biomarkers are currently lacking. This exploratory biomarker analysis of the RAMIRIS trial suggests that elevated baseline and early on‐treatment levels of the pro‐angiogenic placental growth ...
Jurek Hille   +17 more
wiley   +1 more source

Automatic Conversion of NICE Guidelines to an Executable Computational Model Using Large Language Models

open access: yesLearning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Introduction The UK National Institute for Health and Care Excellence (NICE) produce guidelines that provide evidence‐based recommendations to support clinical care across England and Wales, but remain available in unstructured natural language form.
Ashvin Gupta   +3 more
wiley   +1 more source

Gastrointestinal CancerEmerging treatment modalities for gastric cancer with peritoneal metastases: a systematic review. [PDF]

open access: yesOncologist
Tops-Welten MW   +5 more
europepmc   +1 more source

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

open access: yesMolecular Carcinogenesis, Volume 65, Issue 10, Page 1343-1350, October 2026.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla   +7 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier   +37 more
wiley   +1 more source

ASO Author Reflections: The Challenge of Peritoneal Metastases in Patients with Small Bowel Neuroendocrine Tumors. [PDF]

open access: yesAnn Surg Oncol
Chang J   +6 more
europepmc   +1 more source

Transumbilical laparoendoscopic single‐site surgery versus conventional multi‐port laparoscopy for myomectomy: A large single‐center retrospective study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 2068-2080, October 2026.
This retrospective observational study compared clinical outcomes from patients who underwent transumbilical laparoendoscopic single‐site surgery (single‐site laparoscopy) or conventional multi‐port laparoscopy for myomectomy. Single‐site laparoscopy and multi‐port laparoscopy showed similar performance in terms of surgical safety.
Xu Yang   +11 more
wiley   +1 more source

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