Results 221 to 230 of about 288,150 (296)

Paraurethral Endometrioid Carcinoma Arising From Ectopic Endometriosis: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Malignant transformation of endometriosis is rare and most commonly involves the ovary; transformation from paraurethral endometriosis is exceedingly rare. Case Presentation A 73‐year‐old postmenopausal woman with prior ovarian endometrioma presented with dysuria and voiding difficulty.
Keita Ogasawara   +9 more
wiley   +1 more source

Metastatic Urachal Carcinoma With Microsatellite Stability and Low Tumor Mutational Burden Achieving a Durable Response to Pembrolizumab After Platinum Failure

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Urachal carcinoma is a rare and aggressive malignancy with no established systemic therapy after platinum failure. Evidence for immune checkpoint inhibitors (ICIs) remains limited, particularly in tumors without established favorable biomarkers such as microsatellite instability‐high status or high tumor mutational burden.
Fumihiro Ito   +4 more
wiley   +1 more source

Multidisciplinary Treatment of Abdominal Wall Recurrence After Bladder Perforation During Transurethral Resection of a Bladder Tumor

open access: yesIJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Sarcomatoid urothelial carcinoma is a rare, highly aggressive bladder cancer subtype. We report the first case of abdominal wall implantation of sarcomatoid urothelial carcinoma after bladder perforation during transurethral resection of a bladder tumor, followed by recurrence at the open repair site requiring further resection ...
Tomoki Kimura   +8 more
wiley   +1 more source

Tumor‐Associated Mast Cells Drive Immunosuppression and Resistance to Anti‐PD‐1 Therapy in Hepatocellular Carcinoma Through CCL17/CCR4‐mediated Regulatory T‐Cell Recruitment

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Our graphical abstract summarizes a novel immunosuppressive axis in HCC whereby tumor cell‐derived SCF recruits and activates mast cells, leading to CCL17 secretion and subsequent recruitment of CCR4+ regulatory T cells. This cascade suppresses CD8+ T cell‐mediated antitumor immunity and promotes resistance to anti‐PD‐1 therapy.
Shuai Yang, Chuang Yang
wiley   +1 more source

Gastrointestinal CancerEmerging treatment modalities for gastric cancer with peritoneal metastases: a systematic review. [PDF]

open access: yesOncologist
Tops-Welten MW   +5 more
europepmc   +1 more source

The Efferocytosis‐Driven Macrophage Polarization: A Concerto in the Tumor Immunosuppressive Microenvironment

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen   +3 more
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

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