Results 151 to 160 of about 415,778 (252)

A Multidimensional Framework for Interpreting Macrophage Markers in the Era of Cellular Heterogeneity

Immunology, EarlyView.
Macrophage markers should be interpreted as context‐dependent biological readouts rather than deterministic cell identifiers. This Review proposes a multidimensional framework integrating lineage, identity, and functional state across complementary experimental modalities to enable a more accurate interpretation of macrophage heterogeneity.
Alessandro Palma
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

Metastatic organotropism in peritoneal metastasis: Paget's hypothesis revisited. [PDF]

Clin Exp Med
Kim D, Kaushal D, Wilson RB.
europepmc   +1 more source

Comparison of Uncovered and Covered Biliary SEMS for the Salvage of Obstructed SEMS: A Multicenter Retrospective Propensity Score–Weighted Study

Journal of Gastroenterology and Hepatology, EarlyView.
In patients undergoing secondary SEMS placement after initial uncovered stent failure, fully covered and uncovered SEMSs showed comparable patency, survival, and safety. However, mechanisms of recurrent biliary obstruction differed by stent type, with tumor ingrowth in uncovered SEMSs and sludge or food impaction in fully covered SEMSs.
Ho Seung Lee, Gunn Huh, Sung Hyun Cho, Dongwook Oh, Jae Min Lee, Tae Jun Song, Hoonsub So, Hong‐Sik Lee, Dong‐Wan Seo   +8 more
wiley   +1 more source

Early diagnosis and molecular classification of gastric cancer peritoneal metastasis by deep learning-driven single-cell lipidomics. [PDF]

Cell Rep Med
Pan S, Chen X, Xu W, Chen J, Xu K, Gao P, Li Y, Zhao J, Yang J, Du M, Cheng R, Cao J, Li J, Zhao X, Qiao T, Chen T, Li X, Lu C, Xiong S, Yao H, Huang X, Zhang S, Zhang X, Wang Z.   +23 more
europepmc   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

Journal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander, Huile Lim, Gilad Bachrach, Miguel Reis Ferreira   +3 more
wiley   +1 more source

Targeting the remodeled peritoneal ecosystem: a paradigm shift from tumor cells to the microenvironment in gastric cancer peritoneal metastasis. [PDF]

Front Immunol
Gong YX, Hao D, Tan JH, Li LY, Bai J, Feng R.   +5 more
europepmc   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Dynamic cross-linked injectable hydrogel for combined oxaliplatin-resveratrol therapy in colorectal cancer peritoneal metastasis. [PDF]

J Nanobiotechnology
Huang H, Huang H, Zuo C, Yang J, Li H, Jiang F, Li R, Zhang L, Rao S, Ai F, Zong Z, Mao S.   +11 more
europepmc   +1 more source

Far‐field bioluminescent immune cell–mediated photodynamic therapy is limited by photon flux

Photochemistry and Photobiology, EarlyView.
Bioluminescent immune cell‐mediated photodynamic therapy uses tumor‐homing, luciferase‐expressing immune cells as internal light sources to activate photosensitizers in deep‐seated and/or micrometastatic tumors. Using both experiments and computational simulations, we find that this approach delivers insufficient far‐field energy to tumor cells to ...
Ji Tae Park, Sudip Timilsina, Rebecca C. Harman, Chi‐Yong Eom, Jeonghyun Oh, Qianqian Fang, Nozomi Nishimura, Chris B. Schaffer, Bryan Q. Spring   +8 more
wiley   +1 more source