Results 231 to 240 of about 381,959 (294)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Management of gastric cancer peritoneal metastasis: International Gastric Cancer Association GCPM Working Group consensus statements. [PDF]

Br J Surg
Boshier PR, Chia DKA, Thrumurthy SG, Teh JL, Wobith M, Bencivenga M, Filippini F, Dumitra TC, Burch M, Kim HI, Kobitzsch B, Kodach LL, Quik JSE, Long VD, de Neijs MJ, van der Sluis PC, Leon-Takahashi AM, Woo Y, Chevallay M, Framarini M, Morgagni P, Frejlich E, Grabsch HI, Markar SR, Markar SR, Marrelli D, Park DJ, Sundar R, Xu Z, Linn KK, Yang HK, Kitayama J, Zhu Z, Rha SY, Wijnhoven B, Yamashita H, Yong WP, de la Fouchardière C, Nilsson M, Ishigami H, Van Sandick JW, Lordick F, Badgwell BD, So JBY.   +43 more
europepmc   +1 more source

Artificial intelligence‐assisted histopathological diagnosis of endocervical gastric‐type adenocarcinoma: a multicenter model development and validation study

The Journal of Pathology: Clinical Research, Volume 12, Issue 5, September 2026.
Abstract Endocervical gastric‐type adenocarcinoma (GAS) is one of the most aggressive subtypes of cervical cancer and is frequently underdiagnosed due to morphological ambiguity, leading to delayed diagnosis. Despite the availability of molecular and genomic assays, their high cost, complexity, and limited reproducibility restrict clinical use.
Jing Yang, Qiming He, Jing Peng, Yizhi Wang, Jiawen Li, Haoxiang Li, Yan Liu, Yuxiang Wang, Ajin Hu, Xitong Ling, Yingwen Zhang, Minxi Ouyang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Yexing Zhang, Siqi Zeng, Qiang Huang, Zihan Wang, Tian Guan, Yueping Liu, Ling Chen, Yan Ding, Yonghong He, Congrong Liu   +24 more
wiley   +1 more source

Construction of a nomogram for preoperative prediction of occult peritoneal metastasis in advanced gastric cancer based on circulating tumor cells and fibrinogen to albumin ratio. [PDF]

Discov Oncol
Wu Z, Zuo C, Wu C, Tian H, Zhu Z, Zhu W, Sun L, Liu Z.   +7 more
europepmc   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Hyaluronic acid-CD44 signaling defines therapeutic resistance and immunosuppressive microenvironment in peritoneal metastasis of gastric cancer. [PDF]

J Immunother Cancer
Zhao J, Ji C, Sun J, Tian C, Cai T, Wang Z, Sun Z, Li B, Ma G, Liu D, Yamamoto M, Tsukamoto T, Nomura S, Sun L, Sun Y, Huang L, Ruan Y, Li H, Wang X.   +18 more
europepmc   +1 more source

Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang, Jintian Yu, Liang Yuan, Ziliang Fu, Yiming Yao, Lingna Chen, Shixiong Chen, Aikemu Ainiwaer, Xiaolin Cui   +8 more
wiley   +1 more source

Diagnostic Utility of Cytology and Cell Block with Immunohistochemistry in Detection of Peritoneal Metastasis in Gynecological Malignancies. [PDF]

J Cytol
Kaur D, Handa U, Aggarwal P, Goel P.
europepmc   +1 more source

Prevalence of MSI‐H/dMMR Colorectal Cancer in Japan: Data From the Clinical Study Group of the University of Osaka‐Colorectal Registry

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1538-1545, September 2026.
Using a multicenter Japanese colorectal cancer cohort from 25 institutions, we analyzed 1464 patients across all disease stages and tumor locations to determine the prevalence and clinicopathological features of MSI‐H/dMMR colorectal cancer. MSI‐H/dMMR tumors accounted for 9.4% of cases overall, were present in 22% of right‐sided colon cancers, and ...
Yoshihiro Morimoto, Mamoru Uemura, Yoshinori Kagawa, Hidekazu Takahashi, Masayuki Hiraki, Yozo Suzuki, Shinichi Yoshioka, Mitsuyoshi Tei, Shu Okamura, Yukako Mokutani, Atsushi Naito, Shinji Tokuyama, Takamichi Komori, Akinobu Yasuyama, Genta Sawada, Yujiro Fujie, Shinya Yamashita, Naotsugu Haraguchi, Yusuke Matsuura, Chu Matsuda, Yoshinao Chinen, Tatsushi Shingai, Katsuki Danno, Nobuo Tanaka, Kazuya Sakata, Kohei Murata, Yuichiro Doki, Hidetoshi Eguchi   +27 more
wiley   +1 more source

Mitomycin C-Based Hyperthermic Intraperitoneal Chemotherapy Improves Survival in Colorectal Cancer With Peritoneal Metastasis. [PDF]

Cureus
Sirisai C, Moungthard H, Timudom K, Khunpakdee S.   +3 more
europepmc   +1 more source