Results 81 to 90 of about 821,529 (204)

Liquid tumor microenvironment enhances WNT signaling pathway of peritoneal metastasis of gastric cancer

Scientific Reports, 2023
Gastric cancer remains one of the most prevalent tumors worldwide and peritoneal metastasis is responsible for approximately 60% of death in advanced gastric cancer patients. However, the underlying mechanism of peritoneal metastasis is poorly understood.
Huawei Xu, Zhibin Hao, Yujie Wang, Deng Zhang, Jie Li, Ling Chen, Ninghua Yao, Binbin Qian, Xiaobo Peng, Xianbao Zhan   +9 more
doaj   +1 more source

Intraperitoneal chemotherapy for gastric cancer with peritoneal metastasis [PDF]

Gastric Cancer, 2016
Peritoneal metastasis is the most frequent pattern of gastric cancer recurrence or metastasis and is a definitive determinant of prognosis. However, an effective means of treating peritoneal disease has not yet been established. Systemic chemotherapy has only a limited effect on peritoneal metastasis, although some progress has been shown in terms of ...
Daisuke, Kobayashi, Yasuhiro, Kodera
openaire   +2 more sources

Intussusception secondary to a solitary peritoneal lung metastasis [PDF]

BMJ Case Reports, 2013
We report a 77-year-old woman, newly diagnosed with a malignant lung neoplasm of indeterminate nature who presented with profuse bilious vomiting without abdominal distension, pain or constipation. CT confirmed proximal small bowel obstruction. Laparotomy found a large area of intussusception from an intraluminal mass in the small bowel, which was ...
C, Wou, E, Sharp, L, Johnson
openaire   +2 more sources

CD90+ mesothelial-like cells in peritoneal fluid promote peritoneal metastasis by forming a tumor permissive microenvironment. [PDF]

PLoS ONE, 2014
The peritoneal cavity is a common target of metastatic gastrointestinal and ovarian cancer cells, but the mechanisms leading to peritoneal metastasis have not been fully elucidated.
Joji Kitayama, Shigenobu Emoto, Hironori Yamaguchi, Hironori Ishigami, Toshiaki Watanabe   +4 more
doaj   +1 more source

Single-cell RNA-seq analysis of cancer-endothelial cell interactions in primary tumor and peritoneal metastasis from a single patient with colorectal cancer

BJC Reports
Background Peritoneal metastasis, a major complication of colorectal cancer (CRC), often leads to poor quality of life and unfavorable outcomes. Despite numerous studies characterizing its biological features in CRC, intratumor heterogeneity and ...
Yuri Sakimoto, Kohei Kumegawa, Shimpei Matsui, Tomohiro Yamaguchi, Toshiki Mukai, Koji Okabayashi, Seiichi Mori, Yuko Kitagawa, Takashi Akiyoshi, Reo Maruyama   +9 more
doaj   +1 more source

Multidisciplinary Treatment for Colorectal Peritoneal Metastases: Review of the Literature

Gastroenterology Research and Practice, 2016
Peritoneum is one of the common sites of metastasis in advanced stage colorectal cancer patients. Colorectal cancer patients with peritoneal metastases (PM) are traditionally believed to have poor prognosis, which indicates it is of no value to adopt ...
Shaobo Mo, Guoxiang Cai
doaj   +1 more source

Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer

Molecular Therapy: Oncolytics, 2020
Peritoneal metastasis is the most frequent form of distant metastasis and recurrence in gastric cancer, and the prognosis is extremely poor due to the resistance of systemic chemotherapy. Here, we demonstrate that intraperitoneal (i.p.) administration of
Wataru Ishikawa, Satoru Kikuchi, Toshihiro Ogawa, Motoyasu Tabuchi, Hiroshi Tazawa, Shinji Kuroda, Kazuhiro Noma, Masahiko Nishizaki, Shunsuke Kagawa, Yasuo Urata, Toshiyoshi Fujiwara   +10 more
doaj   +1 more source

Investigation of the Japanese Classification of Peritoneal Metastasis from Colorectal Cancer Referring to the Correlation with PCI

Journal of the Anus, Rectum and Colon, 2020
Objectives: In Japan, there are three grades of peritoneal metastasis from colorectal cancer. The grade depends on the extent and number of lesions (P classification). The P classification is useful for its simplicity but lacks objectivity.
Masayasu Kawasaki, Masao Kameyama, Hirotoshi Kobayashi, Kenjiro Kotake, Kenichi Sugihara   +4 more
doaj   +1 more source

The Importance of Extensive Intraoperative Peritoneal Lavage as a Promising Method in Patients with Gastric Cancer Showing Positive Peritoneal Cytology Without Overt Peritoneal Metastasis and Other Therapeutic Approaches

Journal of Investigative Surgery, 2017
Peritoneal invasion is more common and has a worse prognosis in gastric cancer than most of other intestinal cancers. Advanced gastric cancers have a poor course in terms of the development of peritoneal carcinomatosis and prognosis, even if the curative
Enver Ilhan, Ali Alemdar, Orhan Ureyen, Koray Bas   +3 more
doaj   +1 more source

Pathway of peritoneal carcinomatosis maybe hematogenous metastasis rather than peritoneal seeding

Oncotarget, 2017
This study aimed to summarize the clinicopathological data of the cases of gastric cancer or colon cancer with regular metastasis in the mesentery of small intestine and explore the pathway of peritoneal carcinomatosis.We retrospectively analyzed 5 cases of gastric cancer and 3 cases of colon cancer with regular metastasis in the mesentery of the small
Ge, Wei, Chen, Gang, Fan, Xiang-Shan
openaire   +3 more sources