Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. [PDF]
, 2006 Published ...
Dangerfield, J +8 more
core +3 more sources
Journal of Extracellular Vesicles, Volume 14, Issue 8, August 2025.ABSTRACT Despite extensive proof for the tumour‐supporting function of cancer‐derived small extracellular vesicles (sEVs), attributions of pathological effects to specific sEV subpopulations are poorly described. In this study, we aimed to characterise a distinct sEV species under the control of Syntenin, a key regulator of endosomal sEV biogenesis ...
Barnabas Irmer +13 more
wiley +1 more source
One-electron oxidation and reduction of glycosaminoglycan chloramides: a kinetic study. [PDF]
, 2013 Hypochlorous acid and its acid-base counterpart, hypochlorite ions, produced under inflammatory conditions, may produce chloramides of glycosaminoglycans, these being significant components of the extracellular matrix (ECM).
A.W.J. Paterson +67 more
core +1 more source
Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source
European Journal of Histochemistry, 2015 The main purpose of this in situ hybridization study was to investigate mRNA expression of three bone/cartilage matrix components (perlecan, DMP1, and MEPE) in developing primary (tibial) and secondary (condylar) cartilage.
K. Fujikawa +5 more
doaj +1 more source
Specific genes involved in synthesis and editing of heparan sulfate proteoglycans show altered expression patterns in breast cancer [PDF]
, 2013 This work was supported in part by the Instituto de Salud Carlos III-Fondo de Investigación Sanitaria (grant PI051564).
Astudillo González, María Aurora +6 more
core +1 more source
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. [PDF]
, 2006 Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic ...
Bishop, Joseph R +4 more
core +2 more sources
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
eLife, 2019 The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is critical for platelet production and activation. Loss of G6b-B results in severe macrothrombocytopenia, myelofibrosis and aberrant platelet function in mice and humans.
Timo Vögtle +27 more
doaj +1 more source
An Investigation into the Protein Composition of the Teneral Glossina morsitans morsitans Peritrophic Matrix. [PDF]
, 2014 BACKGROUND Tsetse flies serve as biological vectors for several species of African trypanosomes. In order to survive, proliferate and establish a midgut infection, trypanosomes must cross the tsetse fly peritrophic matrix (PM), which is an acellular ...
Acosta-Serrano, Alvaro +7 more
core +4 more sources
The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy. [PDF]
, 2015 During tumor growth and angiogenesis there is a dynamic remodeling of tissue architecture often accompanied by the release of extracellular matrix constituents full of biological activity.
Douglass, Stephen +2 more
core +2 more sources