Results 131 to 140 of about 14,656 (238)

The N‐terminal globular domain of the laminin α1 chain binds to α1β1 and α2β1 integrins and to the heparan sulfate‐containing domains of perlecan [PDF]

, 1998
Norbert Ettner, Walter Göhring, Takako Sasaki, Karlheinz Mann, Rupert Timpl   +4 more
openalex   +1 more source

Changes in glycosaminoglycan structure and composition of the main heparan sulphate proteoglycan from human colon carcinoma cells (perlecan) during cell differentiation [PDF]

, 1998
Anna Molist, Manuel Romarı́s, Ulf Lindahl, Juan Villena, Malika Touab, Anna Bassols   +5 more
openalex   +1 more source

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo. [PDF]

, 1998
Bela Sharma, Melissa Handler, Inge Eichstetter, John M. Whitelock, Matthew A. Nugent, Renato V. Iozzo   +5 more
openalex   +1 more source

Structural insights on perlecan and Schwartz–Jampel syndrome

Matrix Biology
Perlecan is an essential multi-domain, disulfide bond rich basement membrane protein. Mutations in perlecan cause Schwartz-Jampel syndrome and dyssegmental dysplasia. While there has been a large body of experimental work reported on perlecan, there is only minimal structural information available to date. There is no prior structural data for region 3
Anil A. Sohail, M. Kristian Koski, Lloyd W. Ruddock   +2 more
openaire   +2 more sources

Perlecan-Stimulated Nodules Undergo Chondrogenic Maturation in Response to rhBMP-2 Treatment In Vitro [PDF]

, 2003
Ronald R. Gomes, Mary C. Farach Carson, Daniel D. Carson   +2 more
openalex   +2 more sources

Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan [PDF]

, 2001
Marc Kvansakul
openalex   +1 more source

The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔlpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency

Frontiers in Cardiovascular Medicine
IntroductionAscending thoracic aortic aneurysms arise from pathological tissue remodeling that leads to abnormal wall dilation and increases the risk of fatal dissection/rupture. Large variability in disease manifestations across family members who carry
Samar A. Tarraf, Rodrigo Barbosa de Souza, Ashley Herrick, Lygia V. Pereira, Chiara Bellini   +4 more
doaj   +1 more source

Fibroblast Growth Factor-binding Protein Is a Novel Partner for Perlecan Protein Core [PDF]

, 2001
Maurizio Mongiat, Juliet Otto, Rachel A. Oldershaw, Felix Ferrer, J. Denry Sato, Renato V. Iozzo   +5 more
openalex   +1 more source

Heparan Sulfate: A Ubiquitous Glycosaminoglycan with Multiple Roles in Immunity

, 2015
Heparan sulfate (HS) is a highly acidic linear polysaccharide with a very variable structure. It is ubiquitously expressed on cell surfaces and in the extracellular matrix and basement membrane of mammalian tissues.
Parish, Christopher, Simon Davis, David Anak   +1 more
core   +1 more source

The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.

, 1991
Douglas M. Noonan, Anna Fulle, Piera Valente, Silla Cai, Elizabeth A. Horigan, Makoto Sasaki, Yasuhiro Yamada, John R. Hassell   +7 more
openalex   +1 more source