Results 41 to 50 of about 1,422,419 (283)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Characteristics of tight oil in Triassic Yanchang Formation, Ordos Basin

Petroleum Exploration and Development, 2013
By comprehensive study of reservoir and source rock distribution, petrology and geochemistry, the tight oil and its exploration potential was analyzed in the Triassic Yanchang Formation, Ordos Basin.
Jingli YAO, Xiuqin DENG, Yande ZHAO, Tianyou HAN, Meijuan CHU, Jinlian PANG   +5 more
doaj   +1 more source

Synthesis and properties of a new AB-cross-linked copolymer membrane system [PDF]

, 1993
The alcohol permeability and permselectivity properties as well as the morphology of membranes made of a newly developed AB-cross-linked copolymer system composed of elastomeric and glassy components were investigated.
Kerres, J.A., Strathmann, H.
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Optimization of horizontal well injection-production parameters for ultra-low permeable–tight oil production: A case from Changqing Oilfield, Ordos Basin, NW China

Petroleum Exploration and Development, 2015
There are two kinds of displacement mechanisms and three different seepage stages during horizontal well development process with water injection energy.
Jiyong ZHAO, Jianming FAN, Yonghong HE, Ziqing YANG, Wei GAO, Wubin GAO   +5 more
doaj   +1 more source

Numerical upscaling of the permeability of a randomly cracked porous medium [PDF]

, 2008
The equivalent permeability of a randomly cracked porous material is studied using a finite element program in which a four-nodes zero-thickness element is implemented for modelling the cracks.
Ghabezloo, Siavash, Pouya, Ahmad
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Method for Filling Blank Stripes in Electrical Imaging Based on the Fusion of Arbitrary Kernel Convolution and Generative Adversarial Networks

Applied Sciences
Electrical imaging logging images play a crucial role in petroleum exploration; however, in practical applications, blank strips frequently appear due to instrument malfunctions or data transmission failures, severely compromising geological ...
Ruhan A, Die Liu, Ge Cao, Kun Meng, Taiping Zhao, Lili Tian, Bin Zhao, Guilan Lin, Sinan Fang   +8 more
doaj   +1 more source

Field test of volume fracturing for horizontal wells in Sulige tight sandstone gas reservoirs, NW China

Petroleum Exploration and Development, 2014
Based on the development degree of natural micro-fractures, rock brittleness and two-direction stress and other geological conditions of the Sulige gas field, the feasibility of using volume fracturing to increase production was analyzed and verified by ...
Xu MA, Ruifen HAO, Xuan'ang LAI, Yanming ZHANG, Zhanguo MA, Mingfang HE, Yuanxiang XIAO, Man BI, Xinxing MA   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source