Results 51 to 60 of about 2,545,611 (287)

Interaction of Agaric Acid with the Adenine Nucleotide Translocase Induces Mitochondrial Oxidative Stress

Biochemistry Research International, 2020
Mitochondrial permeability transition is characterized by the opening of a transmembranal pore that switches membrane permeability from specific to nonspecific.
Edmundo Chávez, Mabel Buelna-Chontal, Arturo Macías-López, Luz Hernández-Esquivel, Francisco Correa, Natalia Pavón   +5 more
doaj   +1 more source

The mitochondrial permeability transition in neurologic disease [PDF]

Neurochemistry International, 2007
Mitochondria, being the principal source of cellular energy, are vital for cell life. Yet, ironically, they are also major mediators of cell death, either by necrosis or apoptosis. One means by which these adverse effects occur is through the mitochondrial permeability transition (mPT) whereby the inner mitochondrial membrane suddenly becomes ...
M D, Norenberg, K V Rama, Rao
openaire   +2 more sources

Experimental study on the permeability of crushed coal medium based on the Ergun equation

Scientific Reports, 2021
Accurate determination of the permeability of crushed coal medium is the basis for the study of their permeability characteristics. To investigate the permeability characteristics of this special porous medium composed of crushed coal particles, the ...
Mingkun Pang, Tianjun Zhang, Yukai Meng, Zhiqiang Ling   +3 more
doaj   +1 more source

Physiological Roles of the Permeability Transition Pore [PDF]

Circulation Research, 2012
Mitochondria are implicated in many important cellular functions covering the whole life cycle from mitochondrial biogenesis to cell death. Mitochondrial homeostasis is tightly regulated, and mitochondrial dysfunction is frequently associated with severe human pathologies (eg, cardiovascular diseases, cancer, and neurodegeneration).
Catherine, Brenner, Maryline, Moulin
openaire   +2 more sources

Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]

, 2010
An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Schepens, M.A.A., Schepens, Marloes A. A.,, Bovee-Oudenhoven, I.M.J., Brummer, R.J.M., Willemsen, Linette E. M.,, Rijnierse, A., Bovee-Oudenhoven, Ingeborg M. J.,, Schonewille, A.J., Vink, C., Arjan J. Schonewille, Rijnierse, Anneke,, Willemsen, L.E.M., Anneke Rijnierse, Carolien Vink, Marloes A. A. Schepens, Meer, R., van de, Willemsen, L. E., Linette E. M. Willemsen, Vink, Carolien,, Bovee Oudenhoven, I.M., Brummer, R.J., Brummer, Robert,, Roelof van der Meer, van der Meer, Roelof,, van der Meer, R., Ingeborg M. J. Bovee-Oudenhoven, van de Meer, R., Robert-Jan M. Brummer, Schonewille, Arjan J.,   +28 more
core   +1 more source

The permeability transition pore in cell death [PDF]

Apoptosis, 2007
The permeability transition pore (PT-pore) is a multi-component protein aggregate in mitochondria that comprises factors in the inner as well as in the outer mitochondrial membrane. This complex has two functions: firstly, it regulates the integration of oxidative phosphorylation into the cellular energy household and secondly, it induces cell death ...
Stefan, Grimm, Dieter, Brdiczka
openaire   +2 more sources

New advances in the mitochondrial permeability transition Pore structure

, 2018
New advances in the mitochondrial permeability transition Pore ...
M Bonora, M Lebiedzinska, G Morciano, J Duszynski, M Wieckowski, P Pinton, C Giorgi   +6 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection [PDF]

, 2004
Background - Transient (low-conductance) opening of the mitochondrial permeability transition pore (mPTP) may limit mitochondrial calcium load and mediate mitochondrial reactive oxygen species (ROS) signaling.
Wynne, A, Duchen, M, Yellon, D, Hausenloy, D   +3 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source