Results 31 to 40 of about 65,477 (305)
Prostaglandin biosynthesis can be triggered by lipid peroxides [PDF]
Studies of ferriheme cyclooxygenase, using two different assay systems, show that a variety of peroxides can trigger a rapid acceleration of cyclooxygenase activity to produce prostaglandins.
Lands, William E. M. +2 more
core +1 more source
Stochastic protein alkylation by antimalarial peroxides
Antimalarial peroxides such as the phytochemical artemisinin or the synthetic ozonides arterolane and artefenomel undergo reductive cleavage of the pharmacophoric peroxide bond by ferrous heme, released by parasite hemoglobin digestion.
Vennerstrom, Jonathan L. +32 more
core +4 more sources
Alkenyl and aryl peroxides are a special class of organic peroxides. Under ambient conditions, they are usually short‐lived, rapidly decomposing into radicals by homolytic O−O bond cleavage.
Klussmann, M., Martin Klussmann
core +1 more source
The scheme of peroxides activation by ZVI.
The scheme of peroxides activation by ZVI.
Tiancheng Ren (11467473) +6 more
core +1 more source
Synthesis and Asymmetric Resolution of α‑Azido-peroxides
An unprecedented synthesis of α-azido-peroxides has been developed using an FeCl3-catalyst starting from carbonyl, TMS-azide, and hydroperoxide.
Suman Pramanik (1626715) +1 more
core +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Polysorbates, peroxides, protein aggregation, and immunogenicity – a growing concern [PDF]
Aggregation can have a number of deleterious effects on biotherapeutics including the loss of efficacy, the induction of unwanted immunogenicity, altered pharmacokinetics, and reduced shelf life. Aggregation is ameliorated by the inclusion of surfactants
Edward T. Maggio
core
Unveiling an unexpected superoxide-mediated photooxidation mechanism of squalene monohydroperoxides to squalene hydroperoxy cyclic peroxides through ESR and LC-MS/MS analyses [PDF]
Lipid cyclic peroxides are a rarely reported and documented class of compounds in the human organism. Recently, we reported the formation of squalene (SQ) hydroperoxy cyclic peroxides derived from SQ monohydroperoxide isomers (SQ-OOHs) for the first time.
Kiyotaka , Nakagawa +2 more
core +2 more sources
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Reactions of aroyl peroxides. VI. Reactions of mixed peroxides with benzene and nitrobenzene
Reactions of a number of mixed peroxides and mixtures of peroxides, with benzene and with nitrobenzene, have been studied. The complex nature of the reactions prevents quantitative comparison of radicals, but some general features are discussed ...
KH Pausacker, M Mingin
core +1 more source

