Results 51 to 60 of about 543,462 (387)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The protective effect of olive mill pomace (OMP) loaded ethylcellulose microparticles as an alternative to synthetic antioxidants against the oxidation of olive oils was assessed. OMP extract was obtained by an optimized two-step solid-liquid extraction;
Filipa Paulo +2 more
doaj +1 more source
Advances in the synthesis of acyclic peroxides
Peroxide-containing compounds are an attractive synthetic target, given their widespread abundance in nature, with many displaying potent antimalarial and antimicrobial properties.
H. Gandhi +5 more
semanticscholar +1 more source
Hydrogen and carbamide peroxides have been successfully used for many years; in the past century the dental bleaching technique suffered several changes and almost 10 years before new millennium the technique was finally recognized by the international ...
Leandro Feliz-Matos +2 more
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Stable magnesium peroxide at high pressure
Rocky planets are thought to comprise compounds of Mg and O as these are among the most abundant elements, but knowledge of their stable phases may be incomplete.
Goncharov, Alexander F. +6 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
ALKYL IMIDAZOLINES AND THEIR ETHOXYLATED DERIVATIVES AS ANTIOXIDANTS FOR HYDROCARBON PRODUCTS [PDF]
Alkyl imidazolines have been reportedly used in a wide range of industrial formulations with different applications. Ethoxylated alkyl imidazolines with appropriate ethoxylation degrees can be used as antioxidants and retarders in the formation of ...
Daruiosh Farkhani +5 more
doaj +1 more source
Autoxidation of lipids in parchment [PDF]
Historic parchment is a macromolecular material, which is complex due to its natural origin, inhomogeneity of the skin structure, unknown environmental history and potential localised degradation.
Cassar, M. +5 more
core
International Price-Fixing Cartels and Developing Countries: A Discussion of Effects and Policy Remedies [PDF]
The U.S. Department of Justice, the European Commission, and the Organization for Economic Cooperation and Development have all recently voiced concern about international price- fixing cartels. The U.S.
Levenstein, Margaret C. +2 more
core +3 more sources

