Results 61 to 70 of about 105,728 (308)
Oxidative stress in elderly population: A prevention screening study
Aging Medicine, 2020 Background Aging is a multifactorial phenomenon, characterized by a progressive decline in the efficiency of biochemical and physiological processes and an increased susceptibility to disease.
Davide Gorni, Annarosa Finco
doaj +1 more source
Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids [PDF]
, 2009 The pK~a~ estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program.
Kaya Forest +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ingeniería Industrial, 2015 Se evaluó la influencia de dos concentraciones de aceite esencial de orégano: 0,1 % y 0,3 %, aplicados a un aceite de oliva extravirgen con un % de acidez y de índice de peróxido inicial de 0,168 y 9,5 miliequivalente de peróxido/kg, respectivamente ...
Diana Nolazco-Cama +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A Critical Review of Modern Concepts for Teeth Whitening
Dentistry Journal, 2019 Besides prevention of caries and periodontitis, an increasing number of oral care products focus on teeth whitening. The aim of this review is to summarize and discuss frequently used whitening agents and their efficacy from a chemical viewpoint ...
Matthias Epple +2 more
doaj +1 more source
Targeting Lipid Peroxidation for Cancer Treatment
Molecules, 2020 Cancer is one of the highest prevalent diseases in humans. The chances of surviving cancer and its prognosis are very dependent on the affected tissue, body location, and stage at which the disease is diagnosed.
Sofia M. Clemente +3 more
doaj +1 more source
Autoxidation of lipids in parchment [PDF]
, 2009 Historic parchment is a macromolecular material, which is complex due to its natural origin, inhomogeneity of the skin structure, unknown environmental history and potential localised degradation.
Cassar, M. +5 more
core
International Price-Fixing Cartels and Developing Countries: A Discussion of Effects and Policy Remedies [PDF]
, 2003 The U.S. Department of Justice, the European Commission, and the Organization for Economic Cooperation and Development have all recently voiced concern about international price- fixing cartels. The U.S.
Levenstein, Margaret C. +2 more
core +3 more sources