Results 121 to 130 of about 153,107 (266)

Peroxisome calcium uptake is dependent on ER-peroxisome membrane contact. [PDF]

Cell Mol Life Sci
Kalinowski J, Hartmann Y, Lütkemeyer A, Thoms S.   +3 more
europepmc   +1 more source

Systemic Lipid Peroxidation and Colorectal Cancer Risk: A Time‐Varying Relationship

International Journal of Cancer, EarlyView.
Experimental studies in animals suggest that oxidative stress (OxS) declines as cancer progresses. Whether this occurs in humans, however, remains unclear. The authors of the present study addressed this question by analyzing lipid, DNA, and RNA oxidation biomarkers in relation to colorectal cancer (CRC) risk in patients from Shanghai and the United ...
Gong Yang, Ginger L. Milne, Marina S. Nogueira, Yu‐Tang Gao, Qing Lan, Haoyang Yi, Xiao‐Ou Shu, Wei Zheng, Qingxia Chen   +8 more
wiley   +1 more source

PEX11 mediates intralumenal vesicle formation in peroxisomes. [PDF]

Nat Commun
Tharp NE, An C, Hwang J, Shad NS, Wright ZJ, Bartel B.   +5 more
europepmc   +1 more source

Early gut microbial and metabolic dysregulation with subclinical cardiac alterations in a nonhuman primate model of Rett syndrome

iMeta, EarlyView.
Longitudinal multi‐omics profiling of a nonhuman primate Rett syndrome (RTT) model reveals early systemic alterations. RTT monkeys exhibited postnatal growth retardation, intestinal structural abnormalities, and low‐grade systemic inflammation. Gut microbiome analysis showed delayed microbial maturation and age‐discordant dysbiosis, including altered ...
Ting Zhang, Xiaopeng Wang, Peng Li, Junyu Zhang, Wenjie Sun, Zhen Zhang, Yan Zhuo, Wenting Guo, Yongchang Chen   +8 more
wiley   +1 more source

A brief history of the human liver peroxisome. [PDF]

Histochem Cell Biol
De Craemer D, Van den Branden C, Roels F.   +2 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Early hypotonia and visual regression as presenting features of peroxisome biogenesis disorder: an Egyptian case report. [PDF]

BMC Pediatr
Sadek AA, Aladawy MA, Hassan K, Mansour TMM, Naser M, Elmoursy MM, Hedewy S, Hagag A, Mohamed KR, Abdelkreem E.   +9 more
europepmc   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

iNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

Peroxisomes orchestrate metabolic flexibility and longevity via an interorganelle cascade. [PDF]

Nat Aging
Sharma A, Prabhakar A, Valera-Alberni M, Kraft JD, Ellis AE, Sheldon RD, Mistry M, Yao P, Liang Y, Hui S, Mair WB.   +10 more
europepmc   +1 more source

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

Interdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu, Lulu Li, Ying Cao, Ying Wang, Chao Yang, Alexander Nikolaevich Orekhov, Yuanfeng Lu, Houbin Chu, Chuanrong Zhao, Guixue Wang, Guohua Song   +10 more
wiley   +1 more source