Results 201 to 210 of about 261,210 (338)

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Retraction Notice: Anti-kindling Effect of Bezafibrate, a Peroxisome Proliferator-activated Receptors Alpha Agonist, in Pentylenetetrazole Induced Kindling Seizure Model. [PDF]

J Epilepsy Res
Saha L, Bhandari S, Bhatia A, Banerjee D, Chakrabarti A.   +4 more
europepmc   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

Clinical and pathogenetic role of peroxisome proliferator-activated receptor alpha in atherogenesis

, 2012
E. I. Krasilnikova, Anna Kostareva, Dipankar Saha, Sarama Saha, Elena G. Sergeeva, О. А. Беркович, Т. В. Антонова, A.V. Gorbach, Марина Романова, Ж. И. Ионова, А. А. Быстрова, Е. V. Shlyakhto   +11 more
openalex   +1 more source

Activation of peroxisome proliferator‐activated receptor delta suppresses BACE1 expression by up‐regulating SOCS1 in a JAK2/STAT1‐dependent manner [PDF]

, 2019
Won Jin Lee, Sun Ah Ham, Gyeong Hee Lee, Mi‐Jung Choi, Hyunjin Yoo, Kyung Shin Paek, Dae‐Seog Lim, Kwonho Hong, Jung Seok Hwang, Han Geuk Seo   +9 more
openalex   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Move over endosymbionts, peroxisomes pass electrons too. [PDF]

Biochem Soc Trans
Walker BJ, Smith EN, Sweetlove LJ.
europepmc   +1 more source

Gut Microbiota–Metabolism Axis Shapes the Individual Metabolic Phenotype of Different Microbiota‐Accessible Carbohydrates

Food Frontiers, EarlyView.
Specific MAC bioactivities are associated with gut biotransformation. ABSTRACT Increasing the intake of microbiota‐accessible carbohydrates (MACs) has emerged as a promising nutritional strategy for preventing metabolic diseases. However, the consistency of their beneficial effects remains unclear, hindering their optimized application.
Na‐Na Zhang, Guo‐Quan Shao, Xin‐Xin Guo, Jing‐Yi Zhang, Yang Li, Li‐Li Wang, Yue Zhang, Feng‐Zhong Wang, Li‐Tao Tong   +8 more
wiley   +1 more source

PEDV NSP8 inhibits IFN-III production induced by MAVS through downregulation of PEX13. [PDF]

mBio
Lou J, Zhu H, Yang Z, Jiang P, Liu G, Wang X.   +5 more
europepmc   +1 more source

Differentially Expressed Genes (DEGs) Analysis and In Silico Studies Identify Tumor Necrosis Factor (TNF) Inhibition and Peroxisome Proliferator-Activated Receptor Alpha (PPARA) Activation as Targets for Gallic Acid Derivatives in Insulin Resistance

Dwi Anita Suryandari, Aryo Tedjo, Fadilah Fadilah   +2 more
openalex   +2 more sources