Results 201 to 210 of about 310,705 (340)

Pathogenic glycosyltransferase genes and potential therapeutic drugs in pressure overload‐induced heart failure

ESC Heart Failure, EarlyView.
Abstract Aims Protein glycosylation regulated by glycosyltransferases is an important type of post‐translational modification. The role of the glycosyltransferase genes (GTGs) in heart failure (HF) remains unclear and requires further investigation.
Jiahe Wu, Yi Lu, Xinchen Gao, Xiaorong Hu, Zhibing Lu, Chenze Li   +5 more
wiley   +1 more source

Identifying Gene Predictors of Chemicals Linked With Breast Cancer: A Machine Learning Analysis of MCF7 Cellular Transcriptomic Screening Data

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Breast cancer is the most prevalent cancer in women and has been linked to exposure to environmental chemicals. However, many chemicals have not been evaluated for relationships with this outcome. In this study, we analyzed RNA sequencing data from human breast cancer‐derived MCF7 cells exposed to hundreds of individual chemicals.
Lauren E. Koval, Richard Judson, Julia E. Rager   +2 more
wiley   +1 more source

Peroxisomes as emerging clinical targets in neuroinflammatory diseases. [PDF]

Front Mol Neurosci
Roczkowsky A, Rachubinski RA, Hobman TC, Power C.   +3 more
europepmc   +1 more source

Subcellular localization of acyl coenzyme A: dihydroxyacetone phosphate acyltransferase in rat liver peroxisomes (microbodies).

, 1979
A K Hajra, Caryl Burke, Christopher L. Jones   +2 more
openalex   +1 more source

Translocation of acyl-CoA oxidase into peroxisomes requires ATP hydrolysis but not a membrane potential. [PDF]

, 1987
Tsuneo Imanaka, Gillian M. Small, Paul B. Lazarow   +2 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Exploring the Role of Peroxisome-Related Processes and Key Marker Genes in Sepsis: Insights Into Immune Dynamics and Therapeutic Potential. [PDF]

J Inflamm Res
Ye R, Du J, Luo Y.
europepmc   +1 more source

Differential induction of peroxisomal and microsomal fatty‐acid‐oxidising enzymes by peroxisome proliferators in rat liver and kidney [PDF]

, 1989
Rajesh K. Sharma, Brian G. Lake, Richard Makowski, Tony Bradshaw, David L. Earnshaw, Jeremy W. Dale, G. Gordon Gibson   +6 more
openalex   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

Organelle activity organized by the endoplasmic reticulum-mitochondria encounter structure -ERMES- is essential for <i>Podospora anserina</i> development. [PDF]

Microb Cell
Álvarez-Sánchez M, Ramírez-Noguez M, Aguirre-López B, Peraza-Reyes L.   +3 more
europepmc   +1 more source