Results 191 to 200 of about 188,367 (306)

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

Food Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang, Caiyun Feng, Mengyao Zhu, Xu Guo, Yingying Chen, Wenwen Hu, Fei Dong, Jinyue Sun, Chao Liu   +8 more
wiley   +1 more source

Integration of single-cell RNA-sequencing and machine learning identifies GRN and FCER1G as potential peroxisomal targets in influenza pathogenesis. [PDF]

BMC Infect Dis
Shan N, Chen S, Liu Z, Wen Z, Wang J, Yu Y, Liu X, Ning S, Chen H.   +8 more
europepmc   +1 more source

LXRα and PPARα Mediated Hepatic Lipid Metabolic Disruption Induced by the UV Filter EHMC in 2D and 3D HepaRG Cell Models

Food Safety and Health, EarlyView.
Dietary UV filter EHMC induces hepatic steatosis in HepaRG cells at noncytotoxic concentrations. Mechanistically, EHMC binds nuclear receptors (LXRα, PPARα), upregulating SREBP‐1 to accelerate fatty acid synthesis. These findings highlight the potential metabolic toxicity of widespread EHMC exposure through food sources.
Shanglin Yang, Na Li, Yingnan Han, Mei Ma   +3 more
wiley   +1 more source

Saccharomyces cerevisiae malate dehydrogenase Mdh1p lacking mitochondrial targeting signal can be re-localized to peroxisomes

Biology Open
Chutima Chan, Naraporn Sirinonthanawech, Brian K. Sato, James E. Wilhelm, Chalongrat Noree   +4 more
doaj   +1 more source

PEX11 mediates intralumenal vesicle formation in peroxisomes. [PDF]

Nat Commun
Tharp NE, An C, Hwang J, Shad NS, Wright ZJ, Bartel B.   +5 more
europepmc   +1 more source

Gut Microbiota Modulation and Functional Effects of Edible and Medicinal Fungi: Sanghuangporus vaninii as a Case Study

Gut Medicine, EarlyView.
ABSTRACT Edible and medicinal fungi exert diverse biological effects, including immunomodulatory, antitumour, and anti‐inflammatory activities, as well as the amelioration of metabolic disorders. The relationship between these effects and the gut microbiota is attracting increasing attention.
Meng Teng, Wenqi Li, Di Wang, Lanzhou Li
wiley   +1 more source

Peroxisome calcium uptake is dependent on ER-peroxisome membrane contact. [PDF]

Cell Mol Life Sci
Kalinowski J, Hartmann Y, Lütkemeyer A, Thoms S.   +3 more
europepmc   +1 more source

A brief history of the human liver peroxisome. [PDF]

Histochem Cell Biol
De Craemer D, Van den Branden C, Roels F.   +2 more
europepmc   +1 more source

Value of dual energy computed tomography with material decomposition algorithm in assessing intestinal creeping fat in Crohn's disease. [PDF]

World J Radiol
Dong LW, Chen HJ, Chen CC, Lan C.
europepmc   +1 more source

Crosstalk of heat shock proteins and antioxidants with peroxisome biogenesis supports wheat thermotolerance. [PDF]

Sci Rep
Shenoda JE, Sanad MNME, Rizkalla AA, Hussein MH, El-Assal S.   +4 more
europepmc   +1 more source