Results 201 to 210 of about 188,367 (306)

Early hypotonia and visual regression as presenting features of peroxisome biogenesis disorder: an Egyptian case report. [PDF]

open access: yesBMC Pediatr
Sadek AA   +9 more
europepmc   +1 more source

Peroxisomes orchestrate metabolic flexibility and longevity via an interorganelle cascade. [PDF]

open access: yesNat Aging
Sharma A   +10 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

An activity-modulated transport route across myelin (TRAM) for motor-driven organelle transfer in oligodendrocytes. [PDF]

open access: yesNat Neurosci
Chapple KJ   +25 more
europepmc   +1 more source

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

open access: yesiMetaMed, EarlyView.
A pan‐cancer atlas deciphers tumor‐induced reprogramming in bone metastases. Malignant evolution toward MYC/proliferation is a hallmark of bone metastases. Niche‐mediated immune dysfunction is characterized by immature pDCs, impaired antigen presentation and phagocytosis in TAMs, and exhausted T cells.
Yitong Pan   +4 more
wiley   +1 more source

Synthetic cargo adaptors reveal molecular features that enhance dynein activation. [PDF]

open access: yesNat Commun
Siva A   +10 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Peroxisomal Degradation Correlates with the Progression of Kidney Injury in a UUO Mouse Model. [PDF]

open access: yesBiology (Basel)
Kim J   +6 more
europepmc   +1 more source

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