Results 211 to 220 of about 310,705 (340)
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Peroxisomal lipid metabolism inhibits Pimozide-induced cancer cell death by regulating ATP homeostasis. [PDF]
Pan Z +6 more
europepmc +1 more source
DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes. [PDF]
William E. Fahl +4 more
openalex +1 more source
This review emphasizes the critical role of autophagy in cancer treatment, highlighting the development of autophagy‐targeting nanomedicines and their applications in combination therapies. It explores how nanoplatforms can effectively regulate autophagy, underscoring the potential of integrating autophagy modulation with other treatment strategies to ...
Zhouyi Sun +10 more
wiley +1 more source
Protein Kinase C promotes peroxisome biogenesis and peroxisome-endoplasmic reticulum interaction. [PDF]
Borisyuk A +4 more
europepmc +1 more source
Ultrastructural and cytochemical demonstration of peroxisomes in cultured fibroblasts from patients with peroxisomal deficiency disorders. [PDF]
Jonathan Arias +2 more
openalex +1 more source
In this study, Zhang and colleagues show that drinking‐water supplementation of D‐mannose serves as an effective and potential therapeutic of type 2 diabetes, with improvement of both liver health and bone mass. The effect is exerted through suppressing macrophage release of extracellular vesicles based on metabolic control of CD36 expression.
Sha Zhang +21 more
wiley +1 more source
Peroxisome Dysfunction and Steatotic Liver Disease. [PDF]
Vinoy N +3 more
europepmc +1 more source

