Results 211 to 220 of about 310,705 (340)

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

ENZYMES IN PEROXISOMES

open access: bronze, 1973
Estelle J. McGroarty, N. E. Tolbert
openalex   +1 more source

DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes. [PDF]

open access: green, 1984
William E. Fahl   +4 more
openalex   +1 more source

Autophagy‐Targeting Nanomedicine: Strike at the Heart of the Cancer via Precise Modulation of Autophagy

open access: yesExploration, EarlyView.
This review emphasizes the critical role of autophagy in cancer treatment, highlighting the development of autophagy‐targeting nanomedicines and their applications in combination therapies. It explores how nanoplatforms can effectively regulate autophagy, underscoring the potential of integrating autophagy modulation with other treatment strategies to ...
Zhouyi Sun   +10 more
wiley   +1 more source

D‐Mannose Alleviates Type 2 Diabetes and Rescues Multi‐Organ Deteriorations by Controlling Release of Pathological Extracellular Vesicles

open access: yesExploration, EarlyView.
In this study, Zhang and colleagues show that drinking‐water supplementation of D‐mannose serves as an effective and potential therapeutic of type 2 diabetes, with improvement of both liver health and bone mass. The effect is exerted through suppressing macrophage release of extracellular vesicles based on metabolic control of CD36 expression.
Sha Zhang   +21 more
wiley   +1 more source

Peroxisome Dysfunction and Steatotic Liver Disease. [PDF]

open access: yesInt J Mol Sci
Vinoy N   +3 more
europepmc   +1 more source

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