Results 31 to 40 of about 310,705 (340)
Frontiers in Cell and Developmental Biology, 2022 One peculiarity of protists belonging to classes Kinetoplastea and Diplonemea within the phylum Euglenozoa is compartmentalisation of most glycolytic enzymes within peroxisomes that are hence called glycosomes.
Diego Andrade-Alviárez +6 more
doaj +1 more source
Variants of the human PPARG locus and the susceptibility to chronic periodontitis [PDF]
, 2011 Apart from its regulatory function in lipid and glucose metabolism, peroxisome proliferator-activated receptor (PPAR)γ has impact on the regulation of inflammation and bone metabolism.
Desvergne B +5 more
core +1 more source
Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]
, 2014 Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO +7 more
core +2 more sources
A role for peroxisome proliferator-activated receptors in the immunopathology of schistosomiasis? [PDF]
, 2012 Peroxisome proliferator-activated receptors (PPARs) have been demonstrated to have a role in immune regulation. In general, they are anti-inflammatory and promote Th2 type responses, and they are associated with the alternative activation of macrophages.
Allen, JT +3 more
core +4 more sources
Neurophysiological, behavioral and morphological abnormalities in the Fabry knockout mice
Neurobiology of Disease, 2009 Fabry disease (OMIM 301500) is a rare X-linked recessive disorder caused by mutations in the α-galactosidase gene (GLA). Loss of α-galactosidase (α-Gal) activity leads to the abnormal accumulation of glycosphingolipids in lysosomes predominantly of ...
L.G. Rodrigues +7 more
doaj +1 more source
Recent insights into peroxisome biogenesis and associated diseases
Journal of Cell Science, 2020 Peroxisomes are single-membrane organelles present in eukaryotes. The functional importance of peroxisomes in humans is represented by peroxisome-deficient peroxisome biogenesis disorders (PBDs), including Zellweger syndrome.
Y. Fujiki +10 more
semanticscholar +1 more source
Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. [PDF]
, 2010 Peroxisome proliferator-activated receptors (PPARs; PPAR-alpha, PPAR-delta, and PPAR-gamma) comprise a family of nuclear receptors that sense fatty acid levels and translate this information into altered gene transcription.
Axtell, Robert +11 more
core +3 more sources
Molecular Biomarkers for Adrenoleukodystrophy: An Unmet Need
Cells, 2021 X-linked adrenoleukodystrophy (ALD) is an inherited progressive neurometabolic disease caused by mutations in the ABCD1 gene and the accumulation of very long-chain fatty acids in plasma and tissues.
Madison I. J. Honey +4 more
doaj +1 more source
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
Nature Communications, 2018 Nascent lipid droplet (LD) formation occurs in the endoplasmic reticulum (ER) membrane but it is not known how sites of biogenesis are determined. We previously identified ER domains in S. cerevisiae containing the reticulon homology domain (RHD) protein
Amit S. Joshi +6 more
semanticscholar +1 more source
Frontiers in Physiology, 2021 Carnitine palmitoyltransferase II (CPTII) deficiency is the most frequent inherited disorder regarding muscle fatty acid metabolism, resulting in a reduced mitochondrial long-chain fatty acid oxidation during endurance exercise. This condition leads to a
Massimo Negro +9 more
doaj +1 more source