Results 151 to 160 of about 190,211 (348)
Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy [PDF]
, 2010 Jeffrey J. Brault +2 more
openalex +1 more source
Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism
Food Bioengineering, EarlyView.ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing +3 more
wiley +1 more source
trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-α
, 2014 Chunyan Wu +6 more
openalex +1 more source
Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans [PDF]
, 2001 David B. Savage +6 more
openalex +1 more source
Food Frontiers, EarlyView.Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li +8 more
wiley +1 more source
Potential therapeutic effects of peroxisome proliferator-activated receptors on corneal diseases
Experimental Biology and MedicineThe cornea is an avascular tissue in the eye that has multiple functions in the eye to maintain clear vision which can significantly impair one’s vision when subjected to damage.
Bing Jie Chow +5 more
doaj +1 more source
Peroxisome proliferator–activated receptor γ (PPARγ) induces the gene expression of integrin αVβ5 to promote macrophage M2 polarization [PDF]
, 2018 Qinyu Yao +7 more
openalex +1 more source
Food Frontiers, EarlyView.ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang +5 more
wiley +1 more source
Food Frontiers, EarlyView.Specific MAC bioactivities are associated with gut biotransformation. ABSTRACT Increasing the intake of microbiota‐accessible carbohydrates (MACs) has emerged as a promising nutritional strategy for preventing metabolic diseases. However, the consistency of their beneficial effects remains unclear, hindering their optimized application.
Na‐Na Zhang +8 more
wiley +1 more source