Results 271 to 280 of about 190,211 (348)

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Peroxisome proliferator-activated receptor agonists: A new hope towards the management of alcoholic liver disease. [PDF]

World J Gastroenterol
Durairajan SSK, Singh AK, Iyaswamy A.
europepmc   +1 more source

Decoding plant defense signaling using the defenseless mutant

New Phytologist, EarlyView.
Summary Can plants live without defenses? Mutant analysis in Arabidopsis thaliana has identified numerous regulators of biotic, abiotic, and hormone‐based defenses, but the redundancy among separate defense pathways remains unexplored. We constructed an Arabidopsis mutant, defenseless, lacking six canonical defense pathways using abi1‐1 (abscisic acid),
Bikash Baral, Mikael Brosché
wiley   +1 more source

Peroxisome Proliferator-Activated Receptor Gamma Regulates Interleukin-6-Induced Lipoprotein (a) Gene Expression in Human HepG2 Cells. [PDF]

J Cardiovasc Pharmacol
Harb T, Ziogos E, Amat-Alarcon N, Lai S, Gerstenblith G, Arvanitis M, Leucker TM.   +6 more
europepmc   +1 more source

CD36 and Its Role in Obesity

Obesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg   +5 more
wiley   +1 more source

Compound 3d Attenuates Metabolic Dysfunction-Associated Steatohepatitis via Peroxisome Proliferator-Activated Receptor Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling. [PDF]

Metabolites
Zhang S, Yu J, Bai S, Li S, Qiu Q, Kong X, Xiang C, Liu Z, Yu P, Teng Y.   +9 more
europepmc   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, EarlyView.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

Peroxisome proliferator-activated receptor gamma mutation in familial partial lipodystrophy type three: A case report and review of literature. [PDF]

World J Diabetes
Wu CJ, Liu H, Tu LJ, Hu JY.
europepmc   +1 more source

Inflammatory Bowel Disease in Children and Young People Living With Overweight or Obesity: A Critical Narrative Review

Obesity Reviews, EarlyView.
ABSTRACT Inflammatory bowel disease is a chronic inflammatory disorder affecting the gastrointestinal tract. It mainly comprises of Crohn's disease and ulcerative colitis. Its global prevalence has risen simultaneously with overweight and obesity among children and young people over the last decades.
Razan Algarni, Efstathia Papada, Adrian Brown   +2 more
wiley   +1 more source

Acetoacetate Ameliorates Hepatic Fibrosis by Targeting Peroxisome Proliferator-Activated Receptor Gamma to Restore Lipid Droplets in Activated Hepatic Stellate Cells. [PDF]

Pharmaceuticals (Basel)
Zhou Y, Wang F, Hu M, Xia S, Li Y, Zheng S, Zhang F.   +6 more
europepmc   +1 more source