Results 201 to 210 of about 43,085 (313)

Correction to "From Mitochondria to Immunity: The Emerging Roles of Mitochondria-Derived Vesicles and Small Extracellular Vesicles in Cellular Communication and Disease". [PDF]

J Extracell Vesicles
europepmc   +1 more source

Volumetric localization microscopy with deep learning. [PDF]

Nat Commun
Han K, Hua X, Qi T, Gao Z, Wang X, Jia S.   +5 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Microglial forkhead box O3a deficiency attenuates LPS‐induced neuro‐inflammation and depressive‐like behaviour through regulating the expression of peroxisome proliferator‐activated receptor‐γ [PDF]

Rikang Wang, Lianru Ji, Shun Yuan, Xiamin Liu, Zhi Liang, Wenjing Chen, Bocheng Wang, Suifa Hu, Zhiping Liu, Zhiwen Zeng, Yonggui Song, Tao Wu, Baodong Chen   +12 more
openalex   +1 more source

Regulatory mechanisms of reproduction in locusts and grasshoppers

New Plant Protection, EarlyView.
Regulatory networks composed of numerous coding and noncoding genes play crucial roles in the reproduction of locusts and grasshoppers. This review integrates mechanistic advances in reproductive regulation, highlighting environmentally adaptive pathways and providing prospective targets for eco‐friendly pesticides.
Jing He, Jiliang Wang, Xinran Wang
wiley   +1 more source

Peroxisomal integrity in demyelination-associated microglia enables cellular debris clearance and myelin renewal in mice. [PDF]

J Clin Invest
Barnes-Vélez JA, Zhang X, Peña Señeriz YL, Scott KA, Guan Y, Hu J.   +5 more
europepmc   +1 more source

Senescent Mesenchymal Stromal Cells Differentially Alter Adipogenesis in Adipose Tissue, Skeletal Muscle, and Bone Marrow

Obesity, EarlyView.
ABSTRACT Objective Aging alters mesenchymal stromal cell (MSC) function, leading to dysregulated adipogenesis across tissues through biased lineage commitment. Fat redistribution from adipose depots to skeletal muscle and bone marrow is common in aging, but the underlying mechanisms remain unclear.
Xu Zhang, Madison L. Doolittle, Ting Fan, Utkarsh Tripathi, Yan Er Ng, Xinyi Jiang, João F. Passos, Diana Jurk, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Paul D. Robbins, Sundeep Khosla, Nathan K. LeBrasseur   +13 more
wiley   +1 more source

Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites. [PDF]

Sci Rep
Amado L, Percifull L, Franzkoch R, Flatemersch V, Brüggemann EJ, Psathaki OE, Schuldiner M, Bohnert M, Bülow MH, González Montoro A.   +9 more
europepmc   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Peroxisomal Alterations in Prostate Cancer: Metabolic Shifts and Clinical Relevance. [PDF]

Cancers (Basel)
Hussein MAF, Lismont C, Li H, Chai R, Claessens F, Fransen M.   +5 more
europepmc   +1 more source