Results 221 to 230 of about 42,473 (314)

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Using chanarin-dorfman syndrome patient fibroblasts to explore disease mechanisms and new treatment avenues. [PDF]

Orphanet J Rare Dis
Angel M, Kleinberg Y, Newaz T, Li V, Zaid R, Oved K, Dorot O, Pichinuk E, Avitan-Hersh E, Saada A, Weiss K, Zaremberg V, Tal G, Zalckvar E.   +13 more
europepmc   +1 more source

Effect of Extra Virgin Olive Oil High in Bioactive Compounds on Atherosclerosis in Apoe‐Deficient Mice

Molecular Nutrition &Food Research, EarlyView.
EVOO with high content of squalene and the dialdehyde form of decarboxymethyl oleuropein aglycone in HBC consumed by mice reduced atherosclerotic foci and growth of plaques in both sexes. These findings were accompanied by decreases in APOA1, paraoxonase 1, lipoprotein oxidation, expression of CD36 in monocytes, increased differentiation of macrophages
Roberto Martínez‐Beamonte, Cristina Barranquero, Laura Soler, Tania Herrero‐Continente, Anny Carolina Rondón, Carmen Arnal, Gloria Estopañán, Roberto Lasheras, María Jesús Rodriguez‐Yoldi, Joaquín Carlos Surra, Olga Martín‐Belloso, Isabel Odriozola‐Serrano, Jesús Osada, María Ángeles Navarro   +13 more
wiley   +1 more source

Rapamycin-Reactivated Lipid Catabolism in <i>Eruca sativa</i> Mill. Exposed to Salt Stress. [PDF]

Cells
Corti E, Falsini S, Patrussi G, Bazihizina N, Gonnelli C, Papini A.   +5 more
europepmc   +1 more source

Myristic acid utilization in Chinese hamster ovary cells and peroxisome-deficient mutants.

, 1992
Lei‐Guang Wang, Nagender R. Yerram, T L Kaduce, A A Spector   +3 more
openalex   +1 more source

A Global Transcriptomic Analysis Reveals Body Weight‐Specific Molecular Responses to Chronic Orange Juice Consumption in Healthy Individuals

Molecular Nutrition &Food Research, EarlyView.
This study aimed to investigate the molecular pathways involved in the health benefits of chronic orange juice (OJ) consumption through global transcriptomic approach in peripheral blood mononuclear cells (PBMCs). Healthy volunteers consumed 500 mL of OJ daily for 60 days.
Layanne Nascimento Fraga, Dragan Milenkovic, Isabella de Araújo Esteves Duarte, Saivageethi Nuthikattu, Camille Perella Coutinho, Franco Maria Lajolo, Neuza Mariko Aymoto Hassimotto   +6 more
wiley   +1 more source

Peroxisomal membrane protein PMP70 confers drug resistance in colorectal cancer. [PDF]

Cell Death Dis
Yin J, Shao Y, Huang F, Hong Y, Wei W, Jiang C, Zhao Q, Liu L.   +7 more
europepmc   +1 more source

PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes.

, 1994
Martina Marzioch, Ralf Erdmann, Marten Veenhuis, W H Kunau   +3 more
openalex   +1 more source

PPARγ Agonistic Activity of Mimulone and Diplacone Encapsulated in Liposomes and Cyclodextrin Complexes

ChemistryOpen, EarlyView.
Encapsulation of the geranylated flavanones mimulone and diplacone in hydroxypropyl‐β‐cyclodextrins (HP‐β‐CDs) and liposomes is evaluated for their peroxisome proliferator‐activated receptor gamma agonistic activity. While liposomes reduce efficacy, HP‐β‐CDs preserve up to 91.5% of mimulone's activity and mitigate diplacone's cytotoxicity, highlighting
Daniela Nykodýmová, Lenka Molčanová, Jan Kotouček, Josef Mašek, Jakub Treml   +4 more
wiley   +1 more source

ACAA1 knockout increases the survival rate of KPC mice by activating autophagy. [PDF]

Mol Metab
Lee H, Kang M, Sim SH, Kang JH, Choi W, Chun JW, Hong W, Kim C, Ham W, Park JH, Koh EB, Jeon Y, Woo SM, Kim SY.   +13 more
europepmc   +1 more source