Results 91 to 100 of about 46,884 (257)

HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite

open access: yes, 2016
A novel fluorescent probe, HKGreen-3, for sensing peroxynitrite is designed on the basis of the rhodol scaffold and a peroxynitrite-specific oxidation reaction.
Tao Peng (81319), Dan Yang (65758)
core   +1 more source

Emerging insights into amino acid metabolism in the heart: implications for cardiovascular diseases and therapeutic targeting

open access: yesBritish Journal of Pharmacology, EarlyView.
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam   +6 more
wiley   +1 more source

Living in an Oxygen Atmosphere – NO• Problem?

open access: yesCHIMIA, 2001
Formation of nitrogen monoxide in vivo as a signal molecule and as part of the immunological response leads to the formation of oxidized haemoproteins and a powerful oxidant, peroxynitrite.
Susanna Herold, Willem H. Koppenol
doaj  

The fight of innate immunity and abnormal cannabinoids against Candida infection

open access: yesBritish Journal of Pharmacology, EarlyView.
Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori   +2 more
wiley   +1 more source

Anti-Oxidative, Anti-Tumor-Promoting, and<em> </em>Anti-Carcinogensis Activities of Nitroastaxanthin and Nitrolutein, the Reaction Products of Astaxanthin and Lutein with Peroxynitrite

open access: yesMarine Drugs, 2012
Astaxanthin captured peroxynitrite to form nitroastaxanthins. 15-Nitroastaxanthin was a major reaction product of astaxanthin with peroxynitrite. Here, the anti-oxidative, anti-tumor-promoting, and anti-carcinogensis activities of 15-nitroastaxanthin ...
Hideo Etoh   +4 more
doaj   +1 more source

LEISHMANICIDAL ACTIVITY OF PEROXYNITRITE

open access: yes, 2015
Nitric oxide reacts with superoxide to produce peroxynitrite which has been reported to be highly microbicidal to Trypanosoma cruzi in phosphate buffer but ineffective against Leishmania major in culture medium.
KWEE, JK   +3 more
core  

Parasiticidal effects of peroxynitrite on ovine liver flukes in vitro

open access: yes, 2001
Peroxynitrite (ONOO-) is a cytotoxic anion, produced by interaction between nitric oxide and superoxide in vivo in some inflammatory cells. This study investigated its effects on Fasciola hepatica and Dicrocoelium dendriticum isolated from ovine livers ...
G. Sadeghi-Hashjin, S. Naem
core   +1 more source

Peroxynitrite Effects on Smooth Muscle Contractility [PDF]

open access: yes, 2002
Peroxynitrite is formed in blood vessels upon reaction of superoxide anion with nitric oxide (NO). It can oxidize proteins and thiols and nitrosylate free or protein bound thiols and tyrosine residues, thereby producing vascular dysfunction ...
Walia, Mandeep
core   +1 more source

Genetically encoding thyronine for fluorescent detection of peroxynitrite [PDF]

open access: yes, 2020
Peroxynitrite is a highly reactive oxidant effecting cell signaling and cell death. Here we report a fluorescent protein probe to selectively detect peroxynitrite. A novel unnatural amino acid, thyronine (Thy), was genetically encoded in E.
Yang, Bing   +5 more
core   +1 more source

Reactive oxygen species, antioxidants and the regulation of plant development

open access: yesThe FEBS Journal, EarlyView.
The regulation of axillary bud outgrowth by the interplay between phytohormone and redox signals. Axillary bud outgrowth is regulated by cellular energy status and the balance between phytohormones, notably abscisic acid (ABA) and gibberellic acid (GA).
Juwita R. Dewi   +2 more
wiley   +1 more source

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