Results 111 to 120 of about 84,481 (342)

Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity

BMC Neuroscience, 2018
Background Spinal cord injury (SCI) is one of the leading causes of disability and chronic pain. In SCI-induced pathology, homeostasis of the nitric oxide (NO) metabolome is lost. Major NO metabolites such as S-nitrosoglutathione (GSNO) and peroxynitrite
Mushfiquddin Khan, Tajinder S. Dhammu, Inderjit Singh, Avtar K. Singh   +3 more
doaj   +1 more source

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

Identification and quantification of flavonoids in Carica papaya leaf and peroxynitrite-scavenging activity

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To characterize the types, contents, and peroxynitrite-scavenging activities of flavonoids in the leaf of Carica papaya (C. papaya). Methods: Chromatographic and spectroscopic techniques along with high performance liquid chromatography ...
Agung Nugroho, Hesty Heryani, Jae Sue Choi, Hee-Juhn Park   +3 more
doaj   +1 more source

Hydrogen peroxide ‐ responsive aminoferrocene prodrugs

European Journal of Organic Chemistry, Accepted Article.
Aminoferrocene (AF)‐based prodrugs are activated in cancer cells through reactions with H₂O₂ and other reactive oxygen species (ROS), generating electron‐rich AF’s. These, in turn, induce the production of highly toxic O2·‐ and HO·, leading to cancer cell death.
Marlies Körber, Jennifer Rühle, Fabian Halter, Andriy Mokhir   +3 more
wiley   +1 more source

Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration

Redox Biology, 2018
In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine nitration. Peroxynitrite is the product of the diffusion-controlled reaction between superoxide (O2•-) and nitric oxide (•NO). This process is in competition with
Silvina Bartesaghi, Rafael Radi
doaj  

Nitrostative stress status during seasonal and pdmH1N1 infection in Iraq

Journal of Infection in Developing Countries, 2011
Introduction: Influenza A virus infection is associated with oxidative and nitrosative stress. This study aimed to assess nitrosative stress in pandemic H1N1 (pdmH1N1) and seasonal influenza A infected patients.
Marwan S. M. Al-Nimer, Majid M Mahmood, Saba Saadoon Khazaal   +2 more
doaj   +1 more source

Effects of urate, a natural inhibitor of peroxynitrite-mediated toxicity, in the response of Arabidopsis thaliana to the bacterial pathogen Pseudomonas syringae [PDF]

, 2001
Urate, a natural peroxynitrite scavenger, has been used to investígate the possible role of peroxynitrite during plant-pathogen interactions. Urate greatly reduced lesión formation in Arabidopsis leaves treated with an abiotic peroxynitrite-generating ...
Allan, Alvarez, Ausubel, Baker, Balavoine, Beligni, Bennett, Bestwick, Blumwald, Bolwell, Bolwell, Brown, Crawford, Dangl, Delledonne, Durner, Durner, Favey, Foissner, Francisco García-Olmedo, Gardner, Hammond-Kosack, Hooper, Jabs, Josefa M. Alamillo, Kado, Keller, Keogh, Kiedrowski, King, Lagrimini, Lamb, Levine, Lipton, Liu, Lummerzhein, Marla, McLusky, O'Neil, Polle, Pontier, Radi, Regoli, Schubert, Skinner, Stamler, Stamler, Summermatter, Torres, Turner, Uknes, Vasquez-Vivar, Whiteman, Williamson, Wink, Yu   +55 more
core   +2 more sources

Tannin: An Insight into its Cosmeceutical Properties and Uses

Global Challenges, EarlyView.
Filling a gap in the literature, this study identifies the emerging uses of tannin as cosmeceutical ingredient in skin and hair care products. The account offers also a green chemistry, health and economic perspective on future developments concerning the use of tannins in cosmetic products widely employed worldwide such as hair dyes and hair relaxers.
Rosaria Ciriminna, Giovanna Li Petri, Giuseppe Angellotti, Enrica Fontananova, Francesco Meneguzzo, Rafael Luque, Mario Pagliaro   +6 more
wiley   +1 more source

Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis

Asian Journal of Andrology, 2018
Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, its ability to trigger cell ...
Pamela Uribe, María E Cabrillana, Miguel W Fornés, Favián Treulen, Rodrigo Boguen, Vladimir Isachenko, Evgenia Isachenko, Raúl Sánchez, Juana V Villegas   +8 more
doaj   +1 more source

Mechanisms of cell death pathway activation following drug-induced inhibition of mitochondrial complex I

Redox Biology, 2015
Respiratory complex I inhibition by drugs and other chemicals has been implicated as a frequent mode of mitochondria-mediated cell injury. However, the exact mechanisms leading to the activation of cell death pathways are incompletely understood.
Naoki Imaizumi, Kang Kwang Lee, Carmen Zhang, Urs A. Boelsterli   +3 more
doaj   +1 more source