Results 11 to 20 of about 70,974 (235)
Sonochemical formation of peroxynitrite in water: Impact of ultrasonic frequency and power
Ultrasonics Sonochemistry, 2023 There is a lack of literature on peroxynitrite formation due to sonolysis of aerated water. In this work, the impact of sonication parameters, frequency and power, on ultrasonic peroxynitrite production in aerated alkaline water was investigated ...
Hamza Ferkous +2 more
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Frontiers in Cellular Neuroscience, 2022 Glutathione peroxidase 1 (GPX1) is a crucial antioxidant enzyme that prevented the harmful accumulation of intra-cellular hydrogen peroxide. GPX1 might contribute in limiting cochlear damages associated with aging or acoustic overexposure, but the ...
Xue Wang +15 more
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Redox Biology, 2022 The diffusion-limited reaction of nitric oxide (NO) and superoxide (O2−) produces peroxynitrite (ONOO−), a biological oxidant that has been implicated in a number of pathological conditions, including neurodegenerative disorders.
Megan Jandy +17 more
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The protective role of Wnt3a in peroxynitrite-induced damage of cochlear hair cells in vitro
Brazilian Journal of Otorhinolaryngology, 2023 Objective: To investigate the effect of peroxynitrite on the cultured cochlear hair cells of C57BL/6 P3 mice in vitro as well as the role of Wnt3a, as an activator of the canonical Wnt signaling pathway, underlying the action of such an oxidative stress.
Fengyun Cui +3 more
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Protection against peroxynitrite [PDF]
FEBS Letters, 1999 Peroxynitrite formed in vivo from superoxide and nitric oxide can mediate oxidation, nitration, or nitrosation reactions, leading to impaired function, toxicity, and alterations in signaling pathways. Protection against peroxynitrite is important for defense of normal tissue, especially during inflammation.
Arteel, Gavin E. +2 more
openaire +2 more sources
Peroxynitrite decomposition catalysts: Therapeutics for peroxynitrite-mediated pathology [PDF]
Proceedings of the National Academy of Sciences, 1998 Inflamed tissue is often characterized by the production of NO and superoxide. These radicals react at diffusion-limited rates to form the powerful oxidant peroxynitrite (PN). When protonated, PN decomposes into either nitrate or reactive intermediates capable of mediating tissue damage by oxidation of protein, lipid, and nucleic acid.
D, Salvemini +4 more
openaire +2 more sources
FeTPPS, a Peroxynitrite Decomposition Catalyst, Ameliorates Nitrosative Stress in Human Spermatozoa
Antioxidants, 2023 Excessive levels of reactive nitrogen species (RNS), such as peroxynitrite, promote nitrosative stress, which is an important cause of impaired sperm function.
Pamela Uribe +9 more
doaj +1 more source
Antioxidants, 2020 Thiol peroxidases (TP) are ubiquitous and abundant antioxidant proteins of the peroxiredoxin and glutathione peroxidase families that can catalytically and rapidly reduce biologically relevant peroxides, such as hydrogen peroxide and peroxynitrite ...
André Luís Condeles +4 more
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Nitric oxide alleviates cadmium- but not arsenic-induced damages in rice roots [PDF]
, 2020 Nitric oxide (NO) has signalling roles in plant stress responses. Cadmium (Cd) and arsenic (As) soil pollutants alter plant development, mainly the root-system, by increasing NO-content, triggering reactive oxygen species (ROS), and forming peroxynitrite
Altamura, M. M. +6 more
core +1 more source
The Labile Iron Pool Reacts Rapidly and Catalytically with Peroxynitrite
Biomolecules, 2021 While investigating peroxynitrite-dependent oxidation in murine RAW 264.7 macrophage cells, we observed that removal of the Labile Iron Pool (LIP) by chelation increases the intracellular oxidation of the fluorescent indicator H2DCF, so we concluded that
André Luís Condeles +1 more
doaj +1 more source