Crucial role of local peroxynitrite formation in neutrophil-induced endothelial cell activation [PDF]
, 2003 Introduction and methods: The reaction of superoxide anions and NO not only results in a decreased availability of NO, but also leads to the formation of peroxynitrite, the role of which in the cardiovascular system is still discussed controversially. In
Gloe, Torsten +8 more
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Nitric oxide and peroxynitrite in health and disease.
Physiological Reviews, 2007 The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide (NO) has stimulated an extraordinary impetus for scientific research in all the fields of biology and medicine.
P. Pacher, J. Beckman, L. Liaudet
semanticscholar +1 more source
Circulation, 2020 Supplemental Digital Content is available in the text. Background: Impaired endothelium-dependent vasodilation is a hallmark of obesity-induced hypertension.
Matteo Ottolini +16 more
semanticscholar +1 more source
Pros and cons of current approaches for detecting peroxynitrite and their applications
Biomedical Journal, 2014 Peroxynitrite, a representative of reactive nitrogen species, plays important roles in the physiological and pathological processes of many oxidative stress-related diseases.
Xingmiao Chen +3 more
doaj +1 more source
Local oxidative and nitrosative stress increases in the microcirculation during leukocytes-endothelial cell interactions. [PDF]
PLoS ONE, 2012 Leukocyte-endothelial cell interactions and leukocyte activation are important factors for vascular diseases including nephropathy, retinopathy and angiopathy.
Saptarshi Kar, Mahendra Kavdia
doaj +1 more source
Menadione-induced oxidative stress re-shapes the oxylipin profile of Aspergillus flavus and its lifestyle [PDF]
, 2015 Aspergillus flavus is an efficient producer of mycotoxins, particularly aflatoxin B1, probably the most hepatocarcinogenic naturally-occurring compound.
Cigliano, Riccardo Aiese +9 more
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Potential Benefits of Peroxynitrite [PDF]
The Open Pharmacology Journal, 2008 Peroxynitrite (PN) is generated by the reaction of nitric oxide (NO) and superoxide in one of the most rapid reactions in biology. Studies have reported that PN is a cytotoxic molecule that contributes to vascular injury in a number of disease states. However, it has become apparent that PN has beneficial effects including vasodilation, inhibition of ...
Philip J. Kadowitz, Bobby D. Nossaman
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Sonochemical formation of peroxynitrite in water: Impact of ultrasonic frequency and power
Ultrasonics Sonochemistry, 2023 There is a lack of literature on peroxynitrite formation due to sonolysis of aerated water. In this work, the impact of sonication parameters, frequency and power, on ultrasonic peroxynitrite production in aerated alkaline water was investigated ...
Hamza Ferkous +2 more
doaj
Radical Chemistry in a Femtosecond Laser Plasma: Photochemical Reduction of Ag+ in Liquid Ammonia Solution [PDF]
, 2018 Plasmas with dense concentrations of reactive species such as hydrated electrons and hydroxyl radicals are generated from focusing intense femtosecond laser pulses into aqueous media. These radical species can reduce metal ions such as Au3+ to form metal
Ahsan, Syeda +4 more
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Superoxide and peroxynitrite inatherosclerosis. [PDF]
Proceedings of the National Academy of Sciences, 1994 The role of reactive oxygen species in the vascular pathology associated with atherosclerosis was examined by testing the hypothesis that impaired vascular reactivity results from the reaction of nitric oxide (.NO) with superoxide (O2-), yielding the oxidant peroxynitrite (ONOO-).
Sandra H. Gianturco +9 more
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