Results 31 to 40 of about 84,481 (342)

Potential health effects of Champagne wine consumption [PDF]

, 2011
Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of cardiovascular and neurodegenerative disorders.
Corona, Giulia, Garnotel, Roselyne, Gillery, Philippe, Hercelin, Justine, Lovegrove, Julie A., Spencer, Jeremy P. E., Vauzour, David, Williams, Claire M.   +7 more
core   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Changes in IP3 receptor expression and function in aortic smooth muscle of atherosclerotic mice [PDF]

, 2017
Peroxynitrite is an endothelium - independent vasodilator which induces relaxation via membrane hyperpolarisation. A ctivation of IP3 receptors triggers opening of potassium channels and hyperpolarisation.
Alganga, Husman, Almabrouk, Tarek A.M., Currie, Susan, Ewart, Marie-ann, Hubanova, Pavlina, Katwan, Omar J., Kennedy, Simon, Ugusman, Azizah, Vishwanath, Anisha   +8 more
core   +2 more sources

Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation

Redox Biology, 2022
The diffusion-limited reaction of nitric oxide (NO) and superoxide (O2−) produces peroxynitrite (ONOO−), a biological oxidant that has been implicated in a number of pathological conditions, including neurodegenerative disorders.
Megan Jandy, Asra Noor, Pascal Nelson, Cassandra N. Dennys, Isabella M. Karabinas, Jeanine C. Pestoni, Gautam D. Singh, Lam Luc, Rachel Devyldere, Nathalie Perdomo, Catherine E. Mitchell, Levi Adams, Marisa A. Fuse, Francine A. Mendoza, Carrie L. Marean-Reardon, Ryan A. Mehl, Alvaro G. Estevez, Maria Clara Franco   +17 more
doaj  

Genetically encoded fluorescent redox probes. [PDF]

, 2013
Redox processes are involved in almost every cell of the body as a consequence of aerobic life. In the past decades, redox biology has been increasingly recognized as one of the key themes in cell signaling.
Ai, Hui-Wang, Ren, Wei
core   +3 more sources

Primary and secondary oxidative stress in Bacillus [PDF]

, 2011
Coping with oxidative stress originating from oxidizing compounds or reactive oxygen species (ROS), associated with the exposure to agents that cause environmental stresses, is one of the prerequisites for an aerobic lifestyle of Bacillus spp. such as B.
Abee, T., Mols, J.M.
core   +3 more sources

Peroxynitrite decomposition catalyst prevents apoptotic cell death in a human astrocytoma cell line incubated with supernatants of HIV-infected macrophages

BMC Neuroscience, 2002
Background Oxidative stress has shown to contribute in the mechanisms underlying apoptotic cell death occuring in AIDS-dementia complex. Here we investigated the role of peroxynitrite in apoptosis occurring in astroglial cells incubated with supernatants
Perno Carlo, Rotiroti Domenicantonio, Cufari Antonio, Palma Ernesto, Iannone Michelangelo, Paolino Donatella, Salvemini Daniela, Muscoli Carolina, Aquaro Stefano, Mollace Vincenzo   +9 more
doaj   +1 more source

Paradoxical roles of antioxidant enzymes:Basic mechanisms and health implications [PDF]

, 2015
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes.
Amit R. Reddi, Arne Holmgren, Chan PH, Chen EP, Chu FF, Daiber A, Elias S. J. Arnér, Geismann C, Hogan B, Jaarsma D, Jian-Hong Zhu, Jin R, Leitzmann C, Li JJ, Li JJ, Lu YP, Makino N, Miranda-Vizuete A, Mirochnitchenko O, Motoori S, Mulder DW, Ogata M, Oury TD, Papaioannou V, Radi R, Sandbach JM, Takahara S, Thimmulappa RK, Tome ME, Vogel U, Wang F, Wen JK, Wen-Hsing Cheng, Wispe JR, Woychik RP, Xin Gen Lei, Ye-Shih Ho, Yongping Bao, Yoshida T   +38 more
core   +1 more source

Nutraceuticals Targeting Generation and Oxidant Activity of Peroxynitrite May Aid Prevention and Control of Parkinson’s Disease

International Journal of Molecular Sciences, 2020
Parkinson’s disease (PD) is a chronic low-grade inflammatory process in which activated microglia generate cytotoxic factors—most prominently peroxynitrite—which induce the death and dysfunction of neighboring dopaminergic neurons.
M. McCarty, A. Lerner
semanticscholar   +1 more source

The protective role of Wnt3a in peroxynitrite-induced damage of cochlear hair cells in vitro

Brazilian Journal of Otorhinolaryngology, 2023
Objective: To investigate the effect of peroxynitrite on the cultured cochlear hair cells of C57BL/6 P3 mice in vitro as well as the role of Wnt3a, as an activator of the canonical Wnt signaling pathway, underlying the action of such an oxidative stress.
Fengyun Cui, Zhimin Cao, Qianru Zhang, Zhixin Cao   +3 more
doaj